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CHEMBL223494 (CID 44422461) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Unspecified(3)
 
 
Top Targets:
Neur chan LBD(1)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103515198]
Ki 0.00087Displacement of [125I]iodoMLA from alpha-7 nAChR in rat cerebral cortex [AID284638, Type: Literature]Neuronal acetylcholine receptor subunit alpha-7 [gi:146345356]
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2
[SID103515198]
Ki 0.739Displacement of [3H]epibatidine from nAChRalpha, beta in rat cerebral cortex [AID284639, Type: Literature]
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3
[SID103515198]
Antagonism of nicotine-induced seizures in sc dosed ICR mouse [AID284640, Type: Literature]
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4
[SID103515198]
Antagonism of nicotine-induced antinociceptive effect in sc dosed mouse by tail flick assay [AID284642, Type: Literature]
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5
[SID103515198]
Antagonism of nicotine-induced effect in mouse at 20 mg/kg, sc by hot plate assay [AID284644, Type: Literature]
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