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CHEMBL424746 (CID 44413928) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Unspecified(1)
 
 
Top Targets:
RNase RNase-L(2)
 
 
 
BioAssay Types:
Literature(3)
 
 
 
BioActivity Types:
EC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103494006]
EC50 0.0013Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7) [AID266757, Type: Literature]2-5A-dependent ribonuclease [gi:20141791]
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2
[SID103494006]
Stability in mouse spleen assessed as ability to resist degradation by nuclease [AID266759, Type: Literature]
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3
[SID103494006]
Displacement of pA4[32P]pCp from mouse spleen RNase L at 1 uM [AID266756, Type: Literature]2-5A-dependent ribonuclease [gi:20141791]
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