CHEMBL377463
(CID
44413583
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
2
)
Top Targets:
PTKc Abl(
2
)
BioAssay Types:
Literature(
2
)
BioActivity Types:
EC50(
1
)
IC50(
1
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 2 Data Row: 2 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103492918
]
Active
IC50
0.15
Inhibition of c-ABL [AID
266584
, Type: Literature]
Tyrosine-protein kinase ABL1 [gi:
85681908
]
View
X
Row No.
1
Structure
Substance
SID
103492918
CID
44413583
Outcome
Active
IC50
0.15 [uM]
BioAssay
Inhibition of c-ABL
AID
266584
BioAssay type
Literature
Target
Tyrosine-protein kinase ABL1 [gi:
85681908
]
PubMed
16678414
Data Table
2
[SID
103492918
]
Active
IC50
0.15
Inhibition of c-ABL [AID
266584
, Type: Literature]
Tyrosine-protein kinase ABL1 [gi:
85681908
]
View
X
Row No.
2
Structure
Substance
SID
103492918
CID
44413583
Outcome
Active
IC50
0.15 [uM]
BioAssay
Inhibition of c-ABL
AID
266584
BioAssay type
Literature
Target
Tyrosine-protein kinase ABL1 [gi:
85681908
]
PubMed
16678414
Data Table
3
[SID
103492918
]
Active
EC50
0.56
Antiproliferative activity against K562 cells expressing Bcr-Abl [AID
266585
, Type: Literature]
Tyrosine-protein kinase ABL1 [gi:
85681908
]
View
X
Row No.
3
Structure
Substance
SID
103492918
CID
44413583
Outcome
Active
EC50
0.56 [uM]
BioAssay
Antiproliferative activity against K562 cells expressing Bcr-Abl
AID
266585
BioAssay type
Literature
Target
Tyrosine-protein kinase ABL1 [gi:
85681908
]
PubMed
16678414
Data Table
4
[SID
103492918
]
Active
EC50
0.56
Antiproliferative activity against K562 cells expressing Bcr-Abl [AID
266585
, Type: Literature]
Tyrosine-protein kinase ABL1 [gi:
85681908
]
View
X
Row No.
4
Structure
Substance
SID
103492918
CID
44413583
Outcome
Active
EC50
0.56 [uM]
BioAssay
Antiproliferative activity against K562 cells expressing Bcr-Abl
AID
266585
BioAssay type
Literature
Target
Tyrosine-protein kinase ABL1 [gi:
85681908
]
PubMed
16678414
Data Table