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voglibose (CID 444020) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(22)
 
 
Inactive(114)
 
 
Inconclusive(7)
 
 
Unspecified(8)
 
 
Top Targets:
GH31 MGAM SI..(20)
 
 
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
BioAssay Types:
Confirmatory(66)
 
 
 
Literature(29)
 
 
 
Screening(28)
 
 
Summary(24)
 
 
 
BioActivity Types:
Potency(84)
 
 
 
 
IC50(22)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 150    Data Row: 151   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103624146]
IC50 0.07Inhibition of rat intestinal brush border membrane sucrase [AID342797, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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2
[SID103624146]
IC50 0.07Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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3
[SID103624146]
IC50 0.11Inhibition of rat intestinal brush border membrane maltase [AID342793, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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4
[SID103624146]
IC50 0.12Inhibition of rat intestinal maltase using moltose as substrate [AID711104, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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5
[SID103624146]
IC50 0.16Inhibition of rat intestinal brush border membrane isomaltase [AID342795, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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6
[SID103624146]
IC50 0.18Inhibition of Wistar rat small intestine maltase after 30 mins [AID550393, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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7
[SID103624146]
IC50 0.2Inhibition of rat small intestinal sucrase after 30 mins by glucose-oxidase method [AID594100, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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8
[SID103624146]
IC50 0.2Inhibition of rat intestinal sucrase [AID578320, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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9
[SID103624146]
IC50 0.2Inhibition of rat small intestinal maltase after 30 mins [AID593351, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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10
[SID103624146]
IC50 0.37Inhibition of Wistar rat small intestine sucrase after 30 mins [AID550397, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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11
[SID103624146]
IC50 0.37Inhibition of rat intestinal sucrase using sucrose as substrate [AID711102, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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12
[SID103624146]
IC50 1.2Inhibition of rat small intestinal sucrase after 30 mins [AID593349, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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13
[SID103624146]
IC50 1.2Inhibition of rat intestinal maltase [AID578319, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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14
[SID103624146]
IC50 1.2Inhibition of rat small intestinal maltase after 30 mins by glucose-oxidase method [AID594099, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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15
[SID103624146]
IC50 2.1Inhibition of rat small intestinal isomaltase after 30 mins [AID593353, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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16
[SID103624146]
IC50 2.1Inhibition of rat small intestinal isomaltase after 30 mins by glucose-oxidase method [AID594101, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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17
[SID103624146]
IC50 2.1Inhibition of rat intestinal isomaltase [AID578321, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
18
[SID103624146]
IC50 5.2Inhibition of Wistar rat small intestine isomaltase after 30 mins [AID550395, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
19
[SID103624146]
IC50 5.2Inhibition of rat intestinal isomaltase using isomoltose as substrate [AID711103, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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20
[SID103624146]
IC50 5.6Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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21
[SID103624146]
IC50 23.4Inhibition of alpha-glucosidase [AID644400, Type: Literature]
View
22
[SID170465993]
Ratio Potency (uM) 28.7233qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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23
[SID103624146]
IC50 70Inhibition of rabbit muscle amylo-1,6-glucosidase [AID342805, Type: Literature]Glycogen debranching enzyme [gi:544379]
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24
[SID103624146]
Inhibition of Wistar rat small intestine lactase at 1000 uM after 30 mins [AID550399, Type: Literature]Lactase-phlorizin hydrolase [gi:6648054]
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25
[SID103624146]
Inhibition of rabbit glycogen phosphorylase B at 400 uM [AID342804, Type: Literature]
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26
[SID103624146]
Inhibition of Wistar rat small intestine cellobiase at 1000 uM after 30 mins [AID550398, Type: Literature]
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27
[SID103624146]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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28
[SID103624146]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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29
[SID103624146]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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30
[SID103624146]
Inhibition of human lysosomal beta-glucosidase at 1000 uM [AID342802, Type: Literature]Glucosylceramidase [gi:55584151]
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31
[SID136948052]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite H. contortus (hcDAF-12) [AID652067, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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32
[SID136948052]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) [AID652126, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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33
[SID136948052]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the DAF-12 from the parasite H. glycines (hgDAF-12). [AID687014, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
View
34
[SID136948052]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM17. [AID720648, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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35
[SID136948052]
Fluorescence-based biochemical high throughput screening primary assay to identify inhibitors of Crimean-Congo Hemorrhagic Fever (CCHF) viral ovarian tumor domain protease (vOTU): Pep-AMC substrate [AID651958, Type: screening]putative polyprotein [Crimean-Congo hemorrhagic fever virus] [gi:76364066]
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36
[SID136948052]
Fluorescence Intensity-based biochemical primary high throughput screening assay to identify activators of kallikrein-7 (K7) zymogen [AID652039, Type: screening]kallikrein-7 isoform 1 preproprotein [Homo sapiens] [gi:21327705]
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37
[SID136948052]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide [AID686964, Type: screening]Methyl-CpG binding domain protein 2 [Homo sapiens] [gi:21595776]
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38
[SID136948052]
Epi Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2) [AID720702, Type: screening]tyrosyl-DNA phosphodiesterase 2 [Homo sapiens] [gi:23510348]
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39
[SID136948052]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] [AID720508, Type: screening]Chain E, Fragment Double-D From Human Fibrin [gi:28373962]
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40
[SID136948052]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] [AID720509, Type: screening]Chain E, Fragment Double-D From Human Fibrin [gi:28373962]
View
41
[SID136948052]
Primary biochemical fluorescence polarization-based high throughput screening assay to identify inhibitors of protein arginine methyltransferase 1 (PRMT1) [AID652257, Type: screening]PRMT1 protein [Homo sapiens] [gi:32425330]
View
42
[SID144205773]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
43
[SID144205773]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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44
[SID144205773]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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45
[SID144205773]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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46
[SID136948052]
Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID743445, Type: screening]histone-lysine N-methyltransferase NSD2 isoform 1 [Homo sapiens] [gi:109633019]
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47
[SID136948052]
Counterscreen for inhibitors of 5-meCpG-binding domain protein 2 (MBD2): TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of binding of ubiquitin-like with PHD and ring finger domains 1 (UHRF1) to methylated oligonucleotide [AID687016, Type: screening]E3 ubiquitin-protein ligase UHRF1 isoform 1 [Homo sapiens] [gi:115430235]
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48
[SID136948052]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM) [AID652017, Type: screening]SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens] [gi:119579215]
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49
[SID136948052]
QFRET-based biochemical high throughput primary assay to identify inhibitors of human group III secreted phospholipase A2 enzyme (HGIII-sPLA2) [AID743126, Type: screening]phospholipase A2, group III [Homo sapiens] [gi:119580345]
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50
[SID144205773]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
View