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Doxorubicin (CID 443939) - Compound BioActivity Data
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BioActivity Outcomes:
Active(806)
 
 
Inactive(822)
 
 
Inconclusive(180)
 
 
Unspecified(100)
 
 
Top Targets:
NR LBD PPAR(37)
 
 
 
 
NR LBD ER(25)
 
 
 
 
7TM GPCR Srsx(25)
 
 
NR LBD AR(25)
 
 
 
 
7TM GPCR Srx(25)
 
 
 
BioAssay Types:
Confirmatory(639)
 
 
 
 
 
Screening(628)
 
 
 
 
 
Literature(361)
 
 
 
 
 
Summary(63)
 
 
 
 
BioActivity Types:
Potency(538)
 
 
 
 
 
IC50(226)
 
 
 
 
 
EC50(24)
 
 
 
 
AC50(12)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1414    Data Row: 1908   Total Pages: 96   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209681]
Potency-Replicate_1 0.0031qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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2
[SID104234257]
IC50 0.006Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay [AID673199, Type: Literature]
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3
[SID144209681]
Potency-Replicate_1 0.0097qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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4
[SID104234257]
IC50 0.01Cytotoxicity against human KB cells after 48 hrs by MTT assay [AID718784, Type: Literature]
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5
[SID104234257]
IC50 0.01Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay [AID718786, Type: Literature]
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6
[SID104234257]
IC50 0.01Antiproliferative activity against human K562 cells after 48 hrs [AID303684, Type: Literature]
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7
[SID104234257]
IC50 0.01Cytotoxicity against human HL60 cells after 72 hrs by MTT assay [AID333312, Type: Literature]
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8
[SID104234257]
IC50 0.01Antiproliferative activity against human K562 cells after 48 hrs [AID494501, Type: Literature]
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9
[SID104234257]
IC50 0.01Cell growth inhibition of human K562 cells after 48 hrs [AID494520, Type: Literature]
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10
[SID144205614]
Potency-Replicate_1 0.0106qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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11
[SID104234257]
IC50 0.012Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay [AID333313, Type: Literature]
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12
[SID104234257]
IC50 0.017In vitro inhibitory activity against cancerous P388 cell line [AID150546, Type: Literature]
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13
[SID104234257]
EC50 0.02Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay [AID334276, Type: Literature]
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14
[SID104234257]
EC50 0.02Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay [AID334278, Type: Literature]
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15
[SID104234257]
EC50 0.02Antiproliferative activity against mouse 26-L5 cells after 72 hrs by MTT assay [AID334279, Type: Literature]
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16
[SID49718188]
Potency 0.0206qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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17
[SID144209681]
Potency-Replicate_1 0.0243qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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18
[SID104234257]
EC50 0.04Antiproliferative activity against human A549 cells after 72 hrs by MTT assay [AID334277, Type: Literature]
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19
[SID104234257]
GI50 0.06Antitumor activity against human A549 cells after 72 hrs by SRB assay [AID613198, Type: Literature]
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20
[SID104234257]
GI50 0.0603Growth inhibition of human A549 cells after 72 hrs by SRB assay [AID699781, Type: Literature]
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