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CHEMBL73157 (CID 44312236) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(6)
 
 
Inconclusive(1)
 
 
Unspecified(1)
 
 
Top Targets:
PIPKc(1)
 
 
MPP superfami..(1)
 
 
Firefly Luc l..(1)
 
 
PTKc Yes(1)
 
 
BioAssay Types:
Confirmatory(6)
 
 
 
Literature(3)
 
 
 
BioActivity Types:
Potency(8)
 
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 15   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103270888]
IC50 0.04Inhibition of cRaf1 kinase in cascade assay [AID220315, Type: Literature]
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2
[SID124350055]
Potency 0.2067qHTS for Inhibitors of PI5P4K: Confirmation in Primary Assay [AID743286, Type: confirmatory]Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [gi:18266879]
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3
[SID124350055]
Potency 0.4627qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]tyrosine-protein kinase Yes [Homo sapiens] [gi:4885661]
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4
[SID124350055]
Potency 3.1495qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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5
[SID124350055]
Potency 3.1495qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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6
[SID124350055]
Potency 16.3432qHTS Assay for Inhibitors of Sea Pansy Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652015, Type: confirmatory]Renilla-luciferin 2-monooxygenase (EC 1.13.12.5) - sea pansy (Renilla reniformis) (fragment) [Renilla reniformis] [gi:84399]
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7
[SID124350055]
Potency 18.3374qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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8
[SID103270888]
Inhibition of EGF stimulated MAP kinase activation at 15 uM (EGFR phosphorylation unaffected) [AID103030, Type: Literature]
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9
[SID124350055]
Potency 46.2663qHTS for small molecule inhibitors of Yes1 kinase: Counter Assay [AID686950, Type: other]
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10
[SID134352788]
A screen for kinase inhibitors that affect the ability of Pseudomonas aeruginosa to kill Caenorhabditis elegans [AID651566, Type: other]
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11
[SID134352788]
A screen for compounds that activate the pro-inflammatory immune response in murine macrophages [AID652131, Type: other]
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12
[SID134352788]
Screen for IRF3 induction in PMA-stimulated THP1 cells. [AID1053176, Type: other]
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13
[SID134352788]
A screen for known kinase inhibitors that affect liver stage malaria [AID624392, Type: other]
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14
[SID134352788]
A screen for small compounds that change glucocorticoid sensitivity in NFkB suppression [AID624486, Type: other]
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15
[SID124350055]
Potency 12.5385qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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