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BioActivity Data for Compound Staurosporine (CID 44299148)

BioActivity Outcomes:
Active(4)
 
 
Unspecified(1)
 
 
Top Targets:
PTKc VEGFR2(1)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioAssay Categories:
Toxicity(1)
 
 
Cell-based(1)
 
 
BioActivity Types:
EC50(2)
 
 
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103243222]
EC50 0.02975NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay [AID449704, Type: Literature]
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2
[SID103243222]
EC50 0.0547NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay [AID449703, Type: Literature]
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3
[SID103243222]
IC50 0.115Inhibition of Vascular endothelial growth factor receptor 2 (KDR) [AID241651, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
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4
[SID103243222]
CC50 0.355NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) [AID449705, Type: Literature]
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5
[SID103243222]
NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. [AID449706, Type: Literature]
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