ochratoxin A (CID 442530) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(27)
 
 
Inactive(49)
 
 
Inconclusive(20)
 
 
Unspecified(23)
 
 
Top Targets:
MFS(9)
 
 
 
NR LBD TR(6)
 
 
 
 
NR LBD PPAR(5)
 
 
 
 
NR LBD VDR(3)
 
 
 
 
Menin(2)
 
 
BioAssay Types:
Confirmatory(64)
 
 
 
 
Screening(15)
 
 
 
Literature(9)
 
 
 
BioActivity Types:
Potency(62)
 
 
 
 
IC50(3)
 
 
 
Ki(2)
 
 
EC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 109    Data Row: 119   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103724058]
EC50 0.06Induction of apoptosis in human HepG2 cells assessed as caspase 3 activation after 24 hrs by fluorescence assay [AID456116, Type: Literature]
View
2
[SID103724058]
IC50 0.3Cytotoxicity against human HepG2 cells after 48 hrs by WST8 assay [AID456115, Type: Literature]
View
3
[SID26755748]
Potency 0.8913qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
4
[SID26755748]
Potency 0.8913qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
5
[SID26755748]
Potency 0.8913qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
6
[SID26755748]
Potency 0.8913qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
7
[SID26755748]
Potency 0.8913qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View
8
[SID26755748]
Potency 0.8913qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View
9
[SID26755748]
Potency 0.8913qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View
10
[SID26755748]
Potency 0.8913qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View
11
[SID26755748]
Potency 1.9953qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
12
[SID26755748]
Potency 1.9953qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
13
[SID26755748]
Potency 1.9953qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
14
[SID26755748]
Potency 1.9953qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
15
[SID103724058]
Ki 6.30957Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
View
16
[SID26755747]
Potency 22.3872VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
17
[SID26755748]
Potency 39.8107qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling [AID588534, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
18
[SID26755748]
Potency 39.8107qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling [AID588534, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
19
[SID26755748]
Potency 39.8107qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling [AID588534, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
20
[SID26755748]
Potency 44.6684qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway [AID651749, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
21
[SID26755748]
Potency 44.6684qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway [AID651749, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
22
[SID26755748]
Potency 44.6684qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway [AID651749, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
23
[SID26755748]
Potency 44.6684qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway [AID651749, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
24
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling [AID588545, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
25
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling [AID588545, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
26
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling [AID588545, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
27
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
28
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
29
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
30
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
31
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
32
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
33
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
34
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
35
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
36
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
37
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
38
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
39
[SID103724058]
Ki 48.9779Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
View
40
[SID48414248]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
41
[SID48414248]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
42
[SID48414248]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
View
43
[SID48414248]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
44
[SID85844004]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
View
45
[SID26755748]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
View
46
[SID26755748]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
View
47
[SID26755748]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
View
48
[SID26755748]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
View
49
[SID26755748]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
View
50
[SID26755748]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
View