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ochratoxin A (CID 442530) - Compound BioActivity Data
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BioActivity Outcomes:
Active(27)
 
 
Inactive(57)
 
 
Inconclusive(24)
 
 
Unspecified(25)
 
 
Top Targets:
MFS(13)
 
 
 
NR LBD TR(6)
 
 
 
 
NR LBD PPAR(5)
 
 
 
 
KAZAL SLC21(5)
 
 
NR LBD VDR(3)
 
 
 
 
BioAssay Types:
Confirmatory(74)
 
 
 
 
Literature(28)
 
 
 
Screening(17)
 
 
 
BioActivity Types:
Potency(71)
 
 
 
 
IC50(3)
 
 
 
Ki(2)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 118    Data Row: 133   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103724058]
EC50 0.06Induction of apoptosis in human HepG2 cells assessed as caspase 3 activation after 24 hrs by fluorescence assay [AID456116, Type: Literature]
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2
[SID103724058]
IC50 0.3Cytotoxicity against human HepG2 cells after 48 hrs by WST8 assay [AID456115, Type: Literature]
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3
[SID26755748]
Potency 0.8913qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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4
[SID26755748]
Potency 0.8913qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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5
[SID26755748]
Potency 1.9953qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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6
[SID103724058]
Ki 6.30957Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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7
[SID26755747]
Potency 22.3872VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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8
[SID26755748]
Potency 39.8107qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling [AID588534, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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9
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling [AID588545, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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10
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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11
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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12
[SID26755748]
Potency 44.6684qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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13
[SID26755748]
Potency 44.6684qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway [AID651749, Type: confirmatory]nuclear factor NF-kappa-B p105 subunit isoform 1 [Homo sapiens] [gi:34577122]
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14
[SID103724058]
Ki 48.9779Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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15
[SID48414248]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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16
[SID48414248]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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17
[SID48414248]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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18
[SID48414248]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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19
[SID85844004]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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20
[SID26755748]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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