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CHEMBL560382 (CID 44229545) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Unspecified(6)
 
 
Top Targets:
7TM GPCR Srx(1)
 
 
CAP ED(1)
 
 
BioAssay Types:
Literature(10)
 
 
 
BioActivity Types:
IC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 10   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103684716]
IC50 15Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scintillation counting [AID427858, Type: Literature]Neuropeptide Y receptor type 1 [gi:128997]
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2
[SID103684716]
Reduction in starvation-induced food intake in mdr1a deficient CF-1 mouse at 30 mg/kg, ip relative to control [AID427867, Type: Literature]
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3
[SID103684716]
Plasma concentration in mdr1a deficient CF-1 mouse at 30 mg/kg, ip after 30 mins [AID427861, Type: Literature]
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4
[SID103684716]
Plasma concentration in C57BL/6 mouse plasma at 30 mg/kg, ip after 30 mins [AID427864, Type: Literature]
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5
[SID103684716]
IC50 10Displacement of [35S]MK499 from human ERG channel in HEK293 cells [AID427859, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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6
[SID103684716]
Octanol-water distribution coefficient, log D at pH 7.4 [AID427860, Type: Literature]
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7
[SID103684716]
Drug level in C57BL/6 mouse brain at 30 mg/kg, ip after 30 mins [AID427865, Type: Literature]
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8
[SID103684716]
Ratio of drug level in brain to plasma in C57BL/6 mouse at 30 mg/kg, ip after 30 mins [AID427866, Type: Literature]
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9
[SID103684716]
Drug level in mdr1a deficient CF-1 mouse brain at 30 mg/kg, ip after 30 mins [AID427862, Type: Literature]
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10
[SID103684716]
Ratio of drug level in brain to plasma in mdr1a deficient CF-1 mouse at 30 mg/kg, ip after 30 mins [AID427863, Type: Literature]
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