MLS002639482 (CID 44229066) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(147)
 
 
Inconclusive(2)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(8)
 
 
 
7TM GPCR Srsx(4)
 
 
CARD NOD1 CAR..(4)
 
 
 
Chemokine CXC(3)
 
 
 
NR DBD CAR(2)
 
 
BioAssay Types:
Screening(116)
 
 
 
Confirmatory(33)
 
 
 
 
Literature(7)
 
 
 
 
BioActivity Types:
Potency(24)
 
 
 
IC50(12)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 159    Data Row: 159   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85248362]
IC50 2.481SAR analysis of NF-kB dependent luciferase using DAP as an inducer [AID2264, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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2
[SID85248362]
IC50 2.481SAR analysis of NF-kB dependent luciferase using DAP as an inducer [AID2264, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
3
[SID85248362]
IC50 2.65SAR analysis of compounds that inhibit NOD1 revised [AID2333, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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4
[SID85248362]
IC50 2.65SAR analysis of compounds that inhibit NOD1 revised [AID2333, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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5
[SID160698641]
IC50 2.7Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by reporter gene assay [AID655843, Type: Literature]
View
6
[SID85248362]
IC50 3.13SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells [AID2250, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
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7
[SID85248362]
IC50 3.13SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells [AID2250, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
8
[SID85248362]
IC50 3.13SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells [AID2250, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
9
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1) [AID588852, Type: screening]CHRM1 gene product [Homo sapiens] [gi:37622910]
View
10
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1) [AID588852, Type: screening]CHRM1 gene product [Homo sapiens] [gi:37622910]
View
11
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
12
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
13
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
14
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
15
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
16
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
17
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
18
[SID160698641]
IC50 20Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter gene assay [AID655844, Type: Literature]
View
19
[SID160698641]
IC50 20Inhibition of TNFalpha-induced NFkappaB activation in HEK293T cells after 14 hrs by luciferase reporter gene assay [AID655845, Type: Literature]
View
20
[SID160698641]
 Cytotoxicity against HEK293T cells at 20 uM by alamar blue assay [AID655846, Type: Literature]
View
21
[SID85248362]
IC50 5SAR analysis of tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells. [AID2245, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
22
[SID85248362]
IC50 5SAR analysis of tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells. [AID2245, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
23
[SID85248362]
IC50 5SAR analysis of tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells. [AID2245, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
24
[SID85248362]
IC50 5SAR analysis of muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells. [AID2260, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
25
[SID85248362]
IC50 5SAR analysis of muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells. [AID2260, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
26
[SID85248362]
IC50 5SAR analysis of muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells. [AID2260, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
27
[SID85248362]
IC50 20SAR analysis of compounds that are cytotoxic to HEK293 revised [AID2335, Type: confirmatory]
View
28
[SID85248362]
IC50 20SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
29
[SID85248362]
IC50 20SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
30
[SID85248362]
IC50 25SAR analysis of NF-kB dependent luciferase using Doxorucibin as an inducer [AID2255, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
31
[SID85248362]
IC50 25SAR analysis of NF-kB dependent luciferase using Doxorucibin as an inducer [AID2255, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
32
[SID85248362]
IC50 25SAR analysis of NF-kB dependent luciferase using PMA/Ionomycin as an inducer [AID2261, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
33
[SID85248362]
IC50 25SAR analysis of NF-kB dependent luciferase using PMA/Ionomycin as an inducer [AID2261, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
34
[SID99495607]
 uHTS identification of SUMO1-mediated protein-protein interactions [AID602429, Type: screening]SUMO-1 [Homo sapiens] [gi:1762973]
View
35
[SID99495607]
Potency qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
View
36
[SID99495607]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID588352, Type: screening]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
View
37
[SID99495607]
 Identification of inhibitors of RAD54 Measured in Biochemical System Using Plate Reader - 2159-01_Inhibitor_SinglePoint_HTS_Activity [AID602329, Type: screening]RAD54L gene product [Homo sapiens] [gi:216548193]
View
38
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]GALR3 gene product [Homo sapiens] [gi:4503907]
View
39
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]GALR3 gene product [Homo sapiens] [gi:4503907]
View
40
[SID99495607]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1) [AID588354, Type: screening]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
View
41
[SID99495607]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1) [AID588354, Type: screening]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
View
42
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID624267, Type: screening]RIPK2 gene product [Homo sapiens] [gi:4506537]
View
43
[SID99495607]
 Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID624267, Type: screening]RIPK2 gene product [Homo sapiens] [gi:4506537]
View
44
[SID99495607]
 uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay [AID624354, Type: screening]TNFRSF10B gene product [Homo sapiens] [gi:224494019]
View
45
[SID99495607]
 uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay [AID624354, Type: screening]TNFRSF10B gene product [Homo sapiens] [gi:224494019]
View
46
[SID99495607]
 uHTS identification of inhibitors of cullin neddylation in a TR-FRET assay [AID651699, Type: screening]NAE1 gene product [Homo sapiens] [gi:4502169]
View
47
[SID99495607]
 uHTS identification of small molecule activators of alpha dystroglycan glycosylation [AID624168, Type: screening]LARGE [Homo sapiens] [gi:47678551]
View
48
[SID99495607]
 Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID602229, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
49
[SID99495607]
 Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID602229, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
50
[SID99495607]
 Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID602229, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View