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MLS002320365 (CID 44201863) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(375)
 
 
Inconclusive(14)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srsx(14)
 
 
 
7TM GPCR Srx(14)
 
 
Troponin(4)
 
 
RasGEF(4)
 
 
ABCC CFTR1(4)
 
 
BioAssay Types:
Screening(289)
 
 
 
 
Confirmatory(92)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(83)
 
 
 
 
 
IC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 356    Data Row: 396   Total Pages: 20   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85200741]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID85200741]
qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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3
[SID85200741]
Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective antagonists [AID651780, Type: screening]guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens] [gi:156104883]
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4
[SID85200741]
Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective Ga16 agonists [AID651953, Type: screening]guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens] [gi:156104883]
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5
[SID85200741]
Fluorescence-based cell-based primary high throughput confirmation assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID651785, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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6
[SID85200741]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID624466, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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7
[SID85200741]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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8
[SID85200741]
Potency 17.7828qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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9
[SID85200741]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex [AID504707, Type: screening]cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] [gi:6755076]
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10
[SID85200741]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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11
[SID85200741]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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12
[SID85200741]
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
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13
[SID85200741]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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14
[SID85200741]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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15
[SID85200741]
7011-01_Antagonist_SinglePoint_HTS_Activity [AID720647, Type: screening]
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16
[SID85200741]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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17
[SID85200741]
Luminescence-based primary cell-based high throughput screening assay to identify inhibitors of viability of late stage Plasmodium falciparum gametocytes [AID743093, Type: screening]
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18
[SID85200741]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
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19
[SID85200741]
Inhibition of Alexa 488-Fibronectin deposition #on AH1F cell monolayers Measured in Cell-Based System Using Plate Reader - 7059-01_Inhibitor_SinglePoint_HTS_Activity [AID743247, Type: screening]
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20
[SID85200741]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
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