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MLS002320161 (CID 44201684) - Compound BioActivity Data
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BioActivity Outcomes:
Active(35)
 
 
Inactive(364)
 
 
Inconclusive(22)
 
 
Unspecified(9)
 
 
Top Targets:
7tm 4(27)
 
 
Death TRAILR..(12)
 
 
 
 
APOBEC C(5)
 
 
 
Troponin(4)
 
 
CAP ED(4)
 
 
BioAssay Types:
Screening(303)
 
 
 
 
 
Confirmatory(113)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(90)
 
 
 
 
 
AC50(10)
 
 
 
IC50(7)
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 378    Data Row: 430   Total Pages: 22   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85200562]
AC50_uM 0.9556Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
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2
[SID85200562]
AC50_uM 1.563Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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3
[SID85200562]
AbsAC35_uM 4.64Counterscreen for inhibitors of NLG for Luciferase Activators Measured in Cell-Based System Using Plate Reader - 2146-03_Inhibitor_Dose_CherryPick_Activity [AID624404, Type: confirmatory]
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4
[SID85200562]
AbsAC26_uM 4.88Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_Dose_CherryPick_Activity [AID624491, Type: confirmatory]
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5
[SID85200562]
AC50_uM 4.999Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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6
[SID85200562]
Potency 7.3078A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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7
[SID85200562]
AC50_uM 7.823ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
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8
[SID85200562]
Potency 10qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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9
[SID85200562]
Potency 12.5893qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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10
[SID85200562]
Potency 14.1254qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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11
[SID85200562]
EC50_Mean 14.4Dose response counterscreen for uHTS small molecule activators of the adaptive arm of the Unfolded Protein Response via a luminescent-based reporter assay [AID489027, Type: confirmatory]
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12
[SID85200562]
AC50_uM 14.98HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity [AID687027, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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13
[SID85200562]
Potency 16.3601qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen [AID651815, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3F isoform a [Homo sapiens] [gi:22907044]
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14
[SID85200562]
EC50_Mean 18.8Dose response confirmation of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID489032, Type: confirmatory]
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15
[SID85200562]
AC50_uM 33.35PAX8: non-specific cytotoxicity Measured in Cell-Based System Using Plate Reader - 7054-05_Inhibitor_Dose_DryPowder_Activity [AID743021, Type: confirmatory]
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16
[SID85200562]
Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588692, Type: screening]
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17
[SID85200562]
Single concentration confirmation of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID485299, Type: screening]
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18
[SID85200562]
uHTS determination of small molecule cytotoxicity in a fluorescence assay to identify cystic fibrosis induced NFkb Inhibitors [AID602141, Type: screening]
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19
[SID85200562]
uHTS identification of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID449763, Type: screening]
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20
[SID85200562]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
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