Bookmark and Share
MLS002320129 (CID 44201662) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(30)
 
 
Inactive(375)
 
 
Inconclusive(13)
 
 
Unspecified(5)
 
 
Top Targets:
7tm 4(29)
 
 
 
 
ZnMc TACE lik..(6)
 
 
 
ABCC CFTR1(5)
 
 
 
Troponin(4)
 
 
Peptidase C48(4)
 
 
BioAssay Types:
Screening(293)
 
 
 
 
Confirmatory(115)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(92)
 
 
 
 
 
IC50(21)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 373    Data Row: 423   Total Pages: 22   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85200540]
IC50_Mean 1.45Dose Response counterscreen of small molecule antagonists of the CXCR6 receptor using a CXCR5 receptor luminescent beta-arrestin assay [AID651594, Type: confirmatory]C-X-C chemokine receptor type 5 isoform 1 [Homo sapiens] [gi:4502415]
View
2
[SID85200540]
Potency 2.9081qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
View
3
[SID85200540]
IC50_Mean 5.82Dose response confirmation of uHTS hits for small molecule modulators of myocardial damage using 2-dexoy-glucose - Set 2 [AID602210, Type: confirmatory]
View
4
[SID85200540]
Potency 11.1749HTS assay for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1: Hit Confirmation [AID624248, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
View
5
[SID85200540]
Potency 12.5385qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1: Hit Confirmation using MMS Stimulated ELG1 [AID624249, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
View
6
[SID85200540]
Potency 25.929qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
7
[SID85200540]
Potency 25.929qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
8
[SID85200540]
IC50 27.578Dose response confirmation of uHTS hits for small molecule modulators of myocardial damage [AID588779, Type: confirmatory]
View
9
[SID85200540]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
View
10
[SID85200540]
HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
11
[SID85200540]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Full-Length Luciferase Counterscreen assay [AID504607, Type: screening]
View
12
[SID85200540]
uHTS identification of small molecule modulators of myocardial damage [AID588492, Type: screening]
View
13
[SID85200540]
IC50_CXCR6_Mean Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_5, Type: confirmatory]C-C chemokine receptor type 6 [Homo sapiens] [gi:37187860]
View
14
[SID85200540]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM17. [AID720648, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
View
15
[SID85200540]
QFRET-based biochemical high throughput confirmation assay to identify exosite inhibitors of ADAM17 [AID743257, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
View
16
[SID85200540]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID624466, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
View
17
[SID85200540]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) [AID624467, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
View
18
[SID85200540]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]muscarinic acetylcholine receptor M4 [Homo sapiens] [gi:52426748]
View
19
[SID85200540]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View
20
[SID85200540]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View