Myrtillidin
(CID
441774
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
3
)
Unspecified(1)
Top Targets:
Rib hydrolase(
2
)
BioAssay Types:
Literature(
4
)
BioActivity Types:
IC50(
3
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 4 Data Row: 4 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
123086635
]
Active
IC50
16.3
Selectivity ratio of IC50 for human recombinant CD38 to IC50 for Schistosoma mansoni recombinant NAD+ glycohydrolase [AID
537629
, Type: Literature]
View
X
Row No.
1
Structure
Substance
SID
123086635
CID
441774
Outcome
Active
IC50
16.3 [uM]
BioAssay
Selectivity ratio of IC50 for human recombinant CD38 to IC50 for Schistosoma mansoni recombinant NAD+ glycohydrolase
AID
537629
BioAssay type
Literature
Target
PubMed
20951593
Data Table
2
[SID
123086635
]
Active
IC50
37.8
Inhibition of Schistosoma mansoni recombinant NAD+ glycohydrolase expressed in Pichia pastoris by continuous fluorometric method [AID
537627
, Type: Literature]
View
X
Row No.
2
Structure
Substance
SID
123086635
CID
441774
Outcome
Active
IC50
37.8 [uM]
BioAssay
Inhibition of Schistosoma mansoni recombinant NAD+ glycohydrolase expressed in Pichia pastoris by continuous fluorometric method
AID
537627
BioAssay type
Literature
Target
PubMed
20951593
Data Table
3
[SID
123086635
]
Active
IC50
39.2
Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric method [AID
603318
, Type: Literature]
ADP-ribosyl cyclase 1 [gi:
55977782
]
View
X
Row No.
3
Structure
Substance
SID
123086635
CID
441774
Outcome
Active
IC50
39.2 [uM]
BioAssay
Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric method
AID
603318
BioAssay type
Literature
Target
ADP-ribosyl cyclase 1 [gi:
55977782
]
PubMed
21641214
Data Table
4
[SID
123086635
]
Unspecified
Inhibition of human recombinant CD38 expressed in Pichia pastoris by continuous fluorometric method [AID
537628
, Type: Literature]
ADP-ribosyl cyclase 1 [gi:
55977782
]
View
X
Row No.
4
Structure
Substance
SID
123086635
CID
441774
Outcome
Unspecified
BioAssay
Inhibition of human recombinant CD38 expressed in Pichia pastoris by continuous fluorometric method
AID
537628
BioAssay type
Literature
Target
ADP-ribosyl cyclase 1 [gi:
55977782
]
PubMed
20951593
Data Table