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MLS002472305 (CID 44144222) - Compound BioActivity Data
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BioActivity Outcomes:
Active(23)
 
 
Inactive(315)
 
 
Inconclusive(15)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(14)
 
 
7TM GPCR Srsx(10)
 
 
Troponin(6)
 
 
 
APOBEC C(5)
 
 
 
 
RasGEF(4)
 
 
BioAssay Types:
Screening(234)
 
 
 
Confirmatory(105)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(93)
 
 
 
 
 
IC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 314    Data Row: 354   Total Pages: 18   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85149028]
IC50 2.919Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) [AID588341, Type: confirmatory]Beta lactamase [Pseudomonas aeruginosa] [gi:114881106]
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2
[SID85149028]
IC50 3.213Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding [AID588340, Type: confirmatory]toll-like receptor 9 [Homo sapiens] [gi:194068499]
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3
[SID85149028]
Potency 5.8048A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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4
[SID85149028]
Potency 7.3078qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID85149028]
Potency 14.5659qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101: Hit Validation [AID651600, Type: confirmatory]tumor susceptibility gene 101 protein [Homo sapiens] [gi:5454140]
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6
[SID85149028]
Potency 18.3564qHTS for inhibitors of Vif-A3G interactions: Cherry picks [AID651812, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
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7
[SID85149028]
Potency 18.3564qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen [AID651815, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3F isoform a [Homo sapiens] [gi:22907044]
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8
[SID85149028]
Potency 22.3872qHTS for Inhibitors of Vif-A3F Interactions: qHTS [AID602313, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3F isoform a [Homo sapiens] [gi:22907044]
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9
[SID85149028]
Potency 23.1093qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen [AID651813, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
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10
[SID85149028]
Potency 25.1189Inhibitors of USP1/UAF1: Primary Screen [AID743255, Type: confirmatory]USP1 protein, partial [Homo sapiens] [gi:118600387]
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11
[SID85149028]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]troponin I, cardiac muscle [Homo sapiens] [gi:151101270]
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12
[SID85149028]
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding. [AID504734, Type: screening]toll-like receptor 9 [Homo sapiens] [gi:194068499]
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13
[SID85149028]
Fluorescence-based cell-based high throughput confirmation assay for inhibitors of TLR9-MyD88 binding [AID540250, Type: screening]toll-like receptor 9 [Homo sapiens] [gi:194068499]
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14
[SID85149028]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]troponin T, cardiac muscle isoform 3 [Homo sapiens] [gi:48255881]
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15
[SID85149028]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin-releasing hormone receptor 2 [Homo sapiens] [gi:38349113]
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16
[SID85149028]
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR). [AID2435, Type: screening]oxytocin receptor [Homo sapiens] [gi:32307152]
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17
[SID85149028]
Identification of VIF Inhibitors Measured in Cell-Based System Using Imaging - 2108-01_Inhibitor_SinglePoint_HTS_Activity [AID602346, Type: screening]Vif [Human immunodeficiency virus 1] [gi:9629361]
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18
[SID85149028]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of GLD-1 protein - TGE RNA interaction. [AID2280, Type: screening]Protein GLD-1 [Caenorhabditis elegans] [gi:17507875]
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19
[SID85149028]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]troponin C, slow skeletal and cardiac muscles [Homo sapiens] [gi:4507615]
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20
[SID85149028]
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R) [AID2797, Type: screening]vasopressin V1a receptor [Homo sapiens] [gi:4502331]
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