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MLS002302631 (CID 44143838) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(86)
 
 
Top Targets:
alkPPc(4)
 
 
Peptidase C48(3)
 
 
SWIB(2)
 
 
 
Int alpha(2)
 
 
NB-ARC(2)
 
 
BioAssay Types:
Screening(68)
 
 
 
Confirmatory(20)
 
 
Literature(2)
 
 
BioActivity Types:
Potency(16)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 86    Data Row: 90   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85148496]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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2
[SID85148496]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
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3
[SID85148496]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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4
[SID85148496]
uHTS identification of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID449763, Type: screening]
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5
[SID85148496]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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6
[SID85148496]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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7
[SID85148496]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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8
[SID85148496]
Potency qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling [AID493014, Type: confirmatory]
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9
[SID85148496]
Potency qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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10
[SID85148496]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
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11
[SID85148496]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Beta Cell Apoptosis. [AID435005, Type: screening]
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12
[SID85148496]
uHTS luminescence assay for the identification of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID435022, Type: screening]
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13
[SID85148496]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
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14
[SID85148496]
IC50 High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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15
[SID85148496]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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16
[SID85148496]
Image-Based HTS for Selective Agonists for NTR1 [AID493036, Type: screening]neurotensin receptor type 1 [Homo sapiens] [gi:110611243]
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17
[SID85148496]
Potency qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504466, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
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18
[SID85148496]
Potency qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
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19
[SID85148496]
Potency qHTS Assay for the Inhibitors of L3MBTL1 [AID485360, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
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20
[SID85148496]
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504810, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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21
[SID85148496]
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504812, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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22
[SID85148496]
Potency qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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23
[SID85148496]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7) [AID434973, Type: screening]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
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24
[SID85148496]
uHTS Luminescent assay for identification of activators of human intestinal alkaline phosphatase [AID2524, Type: screening]Alkaline phosphatase, intestinal [Homo sapiens] [gi:124376142]
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25
[SID85148496]
uHTS Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase [AID2544, Type: screening]Alkaline phosphatase, intestinal [Homo sapiens] [gi:124376142]
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26
[SID85148496]
HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L isoform 2 precursor [Mus musculus] [gi:124486680]
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27
[SID85148496]
uHTS Luminescent assay for identification of activators of mouse intestinal alkaline phosphatase [AID2805, Type: screening]intestinal alkaline phosphatase precursor [Mus musculus] [gi:124487323]
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28
[SID85148496]
uHTS Luminescent assay for identification of inhibitors of mouse intestinal alkaline phosphatase [AID2806, Type: screening]intestinal alkaline phosphatase precursor [Mus musculus] [gi:124487323]
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29
[SID85148496]
Fluorescence Polarization Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the LANA Histone H2A/H2B Interaction [AID2629, Type: screening]LANA [Human herpesvirus 8] [gi:139472804]
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30
[SID85148496]
RNA aptamer-based HTS for inhibitors of GRK2 [AID488847, Type: screening]beta-adrenergic receptor kinase 1 [Homo sapiens] [gi:148539876]
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31
[SID85148496]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the prolyl oligopeptidase-like enzyme (PREPL) [AID2751, Type: screening]Prolyl endopeptidase-like [Homo sapiens] [gi:153217451]
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32
[SID85148496]
Potency qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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33
[SID85148496]
Fluorescence polarization-based cell-based primary high throughput screening assay to identify inhibitors of insulin-degrading enzyme (IDE) [AID434962, Type: screening]insulin-degrading enzyme isoform 1 [Homo sapiens] [gi:155969707]
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34
[SID85148496]
uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID489030, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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35
[SID85148496]
uHTS Fluorescent assay for identification of activators of Apaf-1 [AID489031, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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36
[SID85148496]
Potency qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID463254, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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37
[SID85148496]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS) [AID485272, Type: screening]protein-arginine deiminase type-4 [Homo sapiens] [gi:216548487]
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38
[SID85148496]
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast [AID2825, Type: screening]NLRP3 protein [Homo sapiens] [gi:219518789]
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39
[SID85148496]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID434989, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
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40
[SID85148496]
FRET-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID485270, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
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41
[SID85148496]
HTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 8 (SENP8) [AID2540, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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42
[SID85148496]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463082, Type: screening]platelet-activating factor acetylhydrolase precursor [Homo sapiens] [gi:270133071]
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43
[SID85148496]
uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent assay [AID463190, Type: screening]TPA: Tim10p [Saccharomyces cerevisiae S288c] [gi:285809906]
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44
[SID85148496]
uHTS identification of small molecule inhibitors of tim10 yeast via a luminescent assay [AID463195, Type: screening]TPA: Tim10p [Saccharomyces cerevisiae S288c] [gi:285809906]
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45
[SID85148496]
uHTS identification of small molecule inhibitors of tim23-1 yeast via a luminescent assay [AID463212, Type: screening]TPA: Tim23p [Saccharomyces cerevisiae S288c] [gi:285814664]
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46
[SID85148496]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis. [AID2462, Type: screening]Chain A, Human Bcl2-A1 In Complex With Bim-Bh3 Peptide [gi:167013344]
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47
[SID85148496]
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity [AID2099, Type: screening]
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48
[SID85148496]
uHTS identification of small molecules that induce b-cell replication in the MIN-6 cell line [AID2380, Type: screening]
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49
[SID85148496]
A yeast HTS for caloric restriction mimetics that inhibit age-related superoxide [AID2690, Type: screening]
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50
[SID85148496]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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