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MLS002630929 (CID 44143705) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(347)
 
 
Inconclusive(15)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(14)
 
 
7TM GPCR Srsx(12)
 
 
Troponin(4)
 
 
RasGEF(4)
 
 
CAP ED(4)
 
 
BioAssay Types:
Screening(246)
 
 
Confirmatory(100)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(86)
 
 
 
 
 
EC50(8)
 
 
 
IC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 323    Data Row: 370   Total Pages: 19   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85148314]
EC50_MICROM 1.449Oxadiazole SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID2009, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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2
[SID87349202]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID87349202]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID85148314]
Dose Response of compounds for six proteins with constant GTP under the condition of Mg buffer [AID2393_6, Type: other]
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5
[SID85148314]
Dose Response of compounds for six proteins with constant GTP under the condition of Mg buffer [AID2393_2, Type: other]
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6
[SID85148314]
Dose Response of compounds for six proteins with constant GTP under the condition of Mg buffer [AID2393_3, Type: other]
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7
[SID85148314]
Dose Response of compounds for six proteins with constant GTP under the condition of Mg buffer [AID2393_4, Type: other]
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8
[SID87349202]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID85148314]
EC50_MICROM 0.305Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID2031, Type: confirmatory]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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10
[SID85148314]
EC50_MICROM 2.104Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant [AID2051, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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11
[SID85148314]
EC50_MICROM 2.535Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID2033, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
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12
[SID87349202]
Potency 14.1254qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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13
[SID85148314]
EC50_MICROM 30Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID2037, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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14
[SID85148314]
EC50_MICROM 30Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype [AID2027, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
View
15
[SID85148314]
EC50_MICROM 30Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant [AID2042, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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16
[SID85148314]
EC50_MICROM 30Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID2053, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
View
17
[SID87349202]
Potency 89.1251qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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18
[SID87349202]
Mycobacterium tuberculosis BioA enzyme inhibitor Measured in Biochemical System Using Plate Reader - 2163-01_Inhibitor_SinglePoint_HTS_Activity [AID602481, Type: screening]bioA [Mycobacterium tuberculosis UT205] [gi:378544807]
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19
[SID87349202]
Potency qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation [AID540263, Type: confirmatory]importin subunit beta-1 isoform 1 [Homo sapiens] [gi:19923142]
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20
[SID87349202]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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