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AGN-PC-071IQN (CID 44142695) - Compound BioActivity Data
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BioActivity Outcomes:
Active(12)
 
 
Inactive(408)
 
 
Inconclusive(9)
 
 
Unspecified(5)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
RasGEF(4)
 
 
Peptidase C48(4)
 
 
alkPPc(4)
 
 
BioAssay Types:
Screening(305)
 
 
 
 
Confirmatory(115)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(95)
 
 
 
 
 
IC50(15)
 
 
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 389    Data Row: 434   Total Pages: 22   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85146839]
Potency 1.4716Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID85146839]
AC50_uM 2.506Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
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3
[SID85146839]
IC50_TAG_Mean 3.89Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_1, Type: confirmatory]
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4
[SID85146839]
AC50_uM 3.991Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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5
[SID85146839]
Potency 4.6109qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID85146839]
IC50_TAG_DAPI_Mean 25Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_4, Type: confirmatory]
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7
[SID85146839]
AbsAC40_uM 29.77HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_Dose_CherryPick_Activity [AID602191, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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8
[SID85146839]
Single concentration confirmation of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651629, Type: screening]
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9
[SID85146839]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
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10
[SID85146839]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
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11
[SID85146839]
uHTS identification of small molecule modulators of myocardial damage [AID588492, Type: screening]
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12
[SID85146839]
HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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13
[SID85146839]
IC50_1_TAG 3.088Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_2, Type: confirmatory]
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14
[SID85146839]
IC50_2_TAG 4.689Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_3, Type: confirmatory]
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15
[SID85146839]
IC50_1_TAG_DAPI 25Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_5, Type: confirmatory]
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16
[SID85146839]
IC50_2_TAG_DAPI 25Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_6, Type: confirmatory]
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17
[SID85146839]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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18
[SID85146839]
IC50_TAG_Mean 3.89Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630, Type: confirmatory]
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19
[SID85146839]
Potency 3.9811qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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20
[SID85146839]
Potency 100HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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