MLS002391695
(CID
44142523
) -
BioAssay Data Summary for Compound
.
Filters:
All Data
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BioActivity Outcomes:
Active(3)
Top Targets:
S14 ClpP 2(
1
)
BioAssay Types:
Confirmatory(
3
)
BioActivity Types:
Potency(
3
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
85146665
]
Active
Potency
2.9362
Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID
504834
, Type: confirmatory]
View
X
Row No.
1
Structure
Substance
SID
85146665
CID
44142523
Outcome
Active
Potency
2.9362 [uM]
BioAssay
Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation
AID
504834
BioAssay type
confirmatory
Target
PubMed
Data Table
2
[SID
85146665
]
Active
Potency
18.3564
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID
686978
, Type: confirmatory]
TDP1 protein [Homo sapiens] [gi:
79154014
]
View
X
Row No.
2
Structure
Substance
SID
85146665
CID
44142523
Outcome
Active
Potency
18.3564 [uM]
BioAssay
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT
AID
686978
BioAssay type
confirmatory
Target
TDP1 protein [Homo sapiens] [gi:
79154014
]
PubMed
Data Table
3
[SID
85146665
]
Active
Potency
18.3564
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID
686978
, Type: confirmatory]
TDP1 protein [Homo sapiens] [gi:
79154014
]
View
X
Row No.
3
Structure
Substance
SID
85146665
CID
44142523
Outcome
Active
Potency
18.3564 [uM]
BioAssay
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT
AID
686978
BioAssay type
confirmatory
Target
TDP1 protein [Homo sapiens] [gi:
79154014
]
PubMed
Data Table
4
[SID
85146665
]
Active
Potency
18.3564
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID
686978
, Type: confirmatory]
TDP1 protein [Homo sapiens] [gi:
79154014
]
View
X
Row No.
4
Structure
Substance
SID
85146665
CID
44142523
Outcome
Active
Potency
18.3564 [uM]
BioAssay
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT
AID
686978
BioAssay type
confirmatory
Target
TDP1 protein [Homo sapiens] [gi:
79154014
]
PubMed
Data Table
5
[SID
85146665
]
Active
Potency
19.9526
qHTS Assay for Activators of ClpP [AID
651965
, Type: confirmatory]
ClpP [Bacillus subtilis] [gi:
2668494
]
View
X
Row No.
5
Structure
Substance
SID
85146665
CID
44142523
Outcome
Active
Potency
19.9526 [uM]
BioAssay
qHTS Assay for Activators of ClpP
AID
651965
BioAssay type
confirmatory
Target
ClpP [Bacillus subtilis] [gi:
2668494
]
PubMed
Data Table