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BioActivity Data for Compound triazolothiadiazine, 31 (CID 44142100)

BioActivity Outcomes:
Active(11)
 
 
Inactive(345)
 
 
Inconclusive(11)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(21)
 
 
Troponin(4)
 
 
RasGEF(4)
 
 
ABCC CFTR1(4)
 
 
alkPPc(4)
 
 
BioAssay Types:
Screening(282)
 
 
 
 
Confirmatory(72)
 
 
 
 
 
Literature(13)
 
 
 
BioActivity Types:
Potency(64)
 
 
 
 
 
IC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 325    Data Row: 368   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103684307]
IC50 0.0098Inhibition of human PDE4A by IMAP fluorescence polarization technology [AID425676, Type: Literature]cAMP-specific 3',5'-cyclic phosphodiesterase 4A [gi:116242706]
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2
[SID124398474]
Potency 8.4368qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds [AID720501, Type: Literature]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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3
[SID85146128]
Potency 12.9953qHTS of GLP-1 Receptor Agonists: Hit Validation [AID743262, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
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4
[SID85146128]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
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5
[SID85146128]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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6
[SID85146128]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
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7
[SID85146128]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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8
[SID85146128]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM) [AID652017, Type: screening]SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens] [gi:119579215]
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9
[SID85146128]
Luminescence-based cell-based primary high throughput confirmation assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM) [AID652260, Type: screening]SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens] [gi:119579215]
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10
[SID85146128]
HTS to Find Inhibitors of Pathogenic Pemphigus Antibodies [AID588358, Type: screening]
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11
[SID85146128]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Full-Length Luciferase Counterscreen assay [AID504607, Type: screening]
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12
[SID85146128]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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13
[SID85146128]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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14
[SID85146128]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ RPL19A_MLPCN. [AID2025, Type: screening]RPL19A [Saccharomyces cerevisiae] [gi:536029]
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15
[SID85146128]
Potency Activators of T cell receptors: qHTS campaign [AID504894, Type: confirmatory]T cell receptor, partial [Homo sapiens] [gi:553160]
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16
[SID85146128]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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17
[SID85146128]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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18
[SID85146128]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493244, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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19
[SID85146128]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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20
[SID85146128]
uHTS identification of antagonists of the CRF-binding protein and CRF-R2 receptor complex [AID588475, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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