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MLS002276503 (CID 44142062) - Compound BioActivity Data
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BioActivity Outcomes:
Active(29)
 
 
Inactive(376)
 
 
Inconclusive(10)
 
 
Unspecified(5)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
ABCC CFTR1(9)
 
 
 
 
7TM GPCR Srsx(7)
 
 
PKc like(6)
 
 
 
PHA02644(4)
 
 
 
BioAssay Types:
Screening(293)
 
 
 
 
Confirmatory(113)
 
 
 
 
 
Literature(13)
 
 
BioActivity Types:
Potency(90)
 
 
 
 
 
IC50(16)
 
 
 
 
AC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 357    Data Row: 420   Total Pages: 21   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85239720]
Potency 0.631Confirmation Assay for Inhibitors of CDC-like Kinase 4 (Kinase-Glo Assay) [AID1970, Type: confirmatory]dual specificity protein kinase CLK4 [Homo sapiens] [gi:10190706]
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2
[SID85239720]
Potency 0.7079Confirmaiton Assay for Inhibitors of CDC-like Kinase 4 (ADP-Glo Assay) [AID1969, Type: confirmatory]dual specificity protein kinase CLK4 [Homo sapiens] [gi:10190706]
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3
[SID85239720]
Potency 0.8913Confirmation Assay for Inhibitors of CDC-like Kinase 4 (ADP-FP Assay) [AID1983, Type: confirmatory]dual specificity protein kinase CLK4 [Homo sapiens] [gi:10190706]
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4
[SID85146089]
Potency 1.6353qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
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5
[SID85146089]
IC50_Mean 1.66Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a PAF-induced IL8 counterscreen [AID624343, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
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6
[SID85146089]
AC50_uM 2.17Inhibitors of Epstein-Barr LMP1 inducible NF-kappaB luciferase reporter Measured in Cell-Based System Using Plate Reader - 2122-01_Inhibitor_Dose_CherryPick_Activity [AID588343, Type: confirmatory]
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7
[SID85239720]
Potency 18.4191Assay for Inhibitors of Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 1A (Kinase-Glo assay): round 2 SAR [AID493206, Type: confirmatory]dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform 1 [Homo sapiens] [gi:18765758]
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8
[SID85239720]
Potency 50.1187qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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9
[SID85146089]
AC50_uM 76.601Lymphoblastoid Cells (LCL) Cytotoxicity Secondary Assay Measured in Cell-Based System Using Plate Reader - 2122-03_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504882, Type: confirmatory]LMP1 [Human herpesvirus 4] [gi:23893668]
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10
[SID85146089]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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11
[SID85146089]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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12
[SID85146089]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format - Set 2 [AID504601, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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13
[SID85146089]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM17. [AID720648, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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14
[SID85146089]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format - Set 2 [AID504601, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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15
[SID85146089]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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16
[SID85146089]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View
17
[SID85146089]
Single concentration confirmation of uHTS hits for cystic fibrosis induced NFkb Inhibitors in a fluoresence assay [AID602472, Type: screening]cystic fibrosis transmembrane conductance regulator [Homo sapiens] [gi:90421313]
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18
[SID85146089]
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay [AID588850, Type: screening]cystic fibrosis transmembrane conductance regulator [Homo sapiens] [gi:90421313]
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19
[SID85146089]
IC50_CF-PAF_Mean Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a panel assay [AID624344_1, Type: confirmatory]cystic fibrosis transmembrane conductance regulator [Homo sapiens] [gi:90421313]
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20
[SID85146089]
Counterscreen for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based high throughput assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16). [AID588824, Type: screening]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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