Bookmark and Share
miglitol (CID 441314) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(37)
 
 
Inactive(439)
 
 
Inconclusive(4)
 
 
Unspecified(48)
 
 
Top Targets:
7tm 4(21)
 
 
GH31 MGAM SI..(20)
 
 
 
NR LBD PPAR(14)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
BioAssay Types:
Screening(227)
 
 
 
 
Confirmatory(181)
 
 
 
 
Literature(81)
 
 
 
 
Summary(24)
 
 
BioActivity Types:
Potency(146)
 
 
 
 
IC50(61)
 
 
 
 
EC50(9)
 
 
Ki(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 492    Data Row: 528   Total Pages: 27   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103582154]
IC50 0.11Inhibition of rat intestinal brush border membrane sucrase [AID342797, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
2
[SID103582154]
Ki 0.13Inhibition of mouse his-tagged ctSI expressed in Sf9 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620763, Type: Literature]
View
3
[SID103582154]
Ki 0.148Inhibition of human ntSI expressed in Drosophila S2 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620764, Type: Literature]
View
4
[SID103582154]
Ki 0.211Inhibition of mouse his-tagged ctMGAM-N2 expressed in Sf9 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620760, Type: Literature]
View
5
[SID103582154]
Ki 0.23Inhibition of mouse his-tagged ctMGAM-N20 expressed in Sf9 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620761, Type: Literature]
View
6
[SID103582154]
IC50 0.35Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
View
7
[SID103582154]
IC50 0.39Inhibition of rabbit muscle amylo-1,6-glucosidase [AID342805, Type: Literature]Glycogen debranching enzyme [gi:544379]
View
8
[SID103582154]
Ki 0.46Competitive inhibition of rat intestinal maltase by Lineweaver-Burk plot analysis [AID710939, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
9
[SID103582154]
IC50 0.5Inhibition of sucrase by HPLC [AID466667, Type: Literature]
View
10
[SID103582154]
IC50 0.59Inhibition of Wistar rat small intestine maltase after 30 mins [AID550393, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
11
[SID103582154]
IC50 1Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
View
12
[SID103582154]
Ki 1Inhibition of human ntMGAM expressed in Drosophila S2 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620762, Type: Literature]
View
13
[SID103582154]
IC50 1Inhibition of Wistar rat small intestine sucrase after 30 mins [AID550397, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
14
[SID103582154]
IC50 1Inhibition of rat intestinal sucrase using sucrose as substrate [AID711102, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
15
[SID103582154]
Ki 1Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assay [AID536212, Type: Literature]Maltase-glucoamylase, intestinal [gi:215274260]
View
16
[SID103582154]
IC50 1.2Inhibition of rat intestinal brush border membrane isomaltase [AID342795, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
17
[SID103582154]
IC50 1.3Inhibition of rat N-terminal maltase-glucoamylase catalytic domain [AID710938, Type: Literature]
View
18
[SID103582154]
IC50 1.3Inhibition of rat intestinal brush border membrane maltase [AID342793, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
19
[SID103582154]
IC50 1.3Inhibition of rat intestinal maltase using moltose as substrate [AID711104, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
20
[SID103582154]
IC50 2Inhibition of lysosomal alpha-glucosidase by HPLC [AID466672, Type: Literature]
View