Bookmark and Share
Netilmicin (CID 441306) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(19)
 
 
Inactive(17)
 
 
Inconclusive(6)
 
 
Unspecified(388)
 
 
Top Targets:
7TM GPCR Srx(17)
 
 
7TM GPCR Srsx(15)
 
 
p450(8)
 
 
NR LBD ER(2)
 
 
STKc ERK1 2 l..(2)
 
 
BioAssay Types:
Literature(295)
 
 
 
 
 
Confirmatory(2)
 
 
BioActivity Types:
IC50(117)
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 430    Data Row: 430   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104234256]
Concentration required for half maximum rate of enhanced [3H]DHS uptake in Escherichia coli K12 [AID65059, Type: Literature]
View
2
[SID104234256]
Lethal dose required to kill 90% of the Escherichia coli K12 (ATCC 25868) cell population [AID65062, Type: Literature]
View
3
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa P21.21 tracheal isolates from mechanically ventilated tuberculosis patient [AID285573, Type: Literature]
View
4
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 65.18-2 tracheal isolates from mechanically ventilated tuberculosis patient [AID285575, Type: Literature]
View
5
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 65.18-3 tracheal isolates from mechanically ventilated tuberculosis patient [AID285576, Type: Literature]
View
6
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 65.18-4 tracheal isolates from mechanically ventilated tuberculosis patient [AID285577, Type: Literature]
View
7
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa P21.23 tracheal isolates from mechanically ventilated tuberculosis patient [AID285578, Type: Literature]
View
8
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa IA5 tracheal isolates from mechanically ventilated tuberculosis patient [AID285579, Type: Literature]
View
9
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa IC7 tracheal isolates from mechanically ventilated tuberculosis patient [AID285580, Type: Literature]
View
10
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 65.33-1 tracheal isolates from mechanically ventilated tuberculosis patient [AID285582, Type: Literature]
View
11
[SID104234256]
Phospholipidosis-positive literature compound observed in rat [AID540237, Type: Literature]
View
12
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 1A9 tracheal isolates from mechanically ventilated tuberculosis patient [AID285594, Type: Literature]
View
13
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 2A2 tracheal isolates from mechanically ventilated tuberculosis patient [AID285599, Type: Literature]
View
14
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 2C2 tracheal isolates from mechanically ventilated tuberculosis patient [AID285600, Type: Literature]
View
15
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 2A3 tracheal isolates from mechanically ventilated tuberculosis patient [AID285601, Type: Literature]
View
16
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 2A5 tracheal isolates from mechanically ventilated tuberculosis patient [AID285602, Type: Literature]
View
17
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 2A1 tracheal isolates from mechanically ventilated tuberculosis patient [AID285597, Type: Literature]
View
18
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 3B1 tracheal isolates from mechanically ventilated tuberculosis patient [AID285608, Type: Literature]
View
19
[SID104234256]
Antimicrobial activity against Pseudomonas aeruginosa 65.68-1 tracheal isolates from mechanically ventilated tuberculosis patient [AID285609, Type: Literature]
View
20
[SID104234256]
Kd 100Displacement of ethdium bromide from human pre-hsa-mir-155 miRNA after 30 mins [AID644960, Type: Literature]
View
21
[SID104234256]
Km 304.2Acetylation activity of AAC(6')-APH(2'') in Escherichia coli BL21(DE3) assessed as production of free pyridine-4-thiolate [AID533622, Type: Literature]
View
22
[SID104234256]
Km 308.2Phosphorylation activity of AAC(6')-APH(2'') in Escherichia coli BL21(DE3) assessed as oxidation of NADH by pyruvate kinase [AID533625, Type: Literature]
View
23
[SID104234256]
Phosphorylation activity of AAC(6')-APH(2'') in Escherichia coli BL21(DE3) assessed as oxidation of NADH by pyruvate kinase relative to verdamicin [AID533626, Type: Literature]
View
24
[SID104234256]
Ratio of Vmax to Km for AAC(6')-APH(2'') in Escherichia coli BL21(DE3) assessed as oxidation of NADH by pyruvate kinase relative to netilmicin [AID533627, Type: Literature]
View
25
[SID104234256]
Antimicrobial activity against rmtB positive Escherichia coli VOG producing beta lactamse CTX-M-14 by Etest method [AID534166, Type: Literature]
View
26
[SID104234256]
Antimicrobial activity against Escherichia coli TOP10 harboring plasmid VOG1 expressing RmtB, TEM-1, and QepA gene by Etest method [AID534167, Type: Literature]
View
27
[SID104234256]
Antimicrobial activity against Escherichia coli TOP10 harboring plasmid VOG2 expressing CTX-M-14 and AAC(6 )-Ib gene by Etest method [AID534168, Type: Literature]
View
28
[SID104234256]
Antimicrobial activity against armB positive Escherichia coli COP producing beta lactamse CTX-M-14 by Etest method [AID534169, Type: Literature]
View
29
[SID104234256]
Antimicrobial activity against armA positive Escherichia coli TOP10 harboring plasmid COP1 by Etest method [AID534170, Type: Literature]
View
30
[SID104234256]
Antimicrobial activity against beta lactamase CTX-M-14 producing Escherichia coli TOP10 harboring plasmid COP2 by Etest method [AID534171, Type: Literature]
View
31
[SID104234256]
Antimicrobial activity against armA positive Escherichia coli MEZ producing beta lactamase CTX-M-3 by Etest method [AID534172, Type: Literature]
View
32
[SID104234256]
Antimicrobial activity against armA positive Escherichia coli TOP10 producing beta lactamase CTX-M-3 with plasmid MEZ by Etest method [AID534173, Type: Literature]
View
33
[SID104234256]
Antimicrobial activity against armA positive Enterobacter cloacae BEH producing beta lactamase CTX-M-3 by Etest method [AID534174, Type: Literature]
View
34
[SID104234256]
Antimicrobial activity against armA positive Escherichia coli TOP10 producing beta lactamase CTX-M-3 with plasmid BEH by Etest method [AID534175, Type: Literature]
View
35
[SID104234256]
Antimicrobial activity against armA positive Klebsiella pneumoniae DU producing beta lactamase CTX-M-3 by Etest method [AID534176, Type: Literature]
View
36
[SID104234256]
Antimicrobial activity against armA positive Escherichia coli TOP10 producing beta lactamase CTX-M-3 with plasmid DU by Etest method [AID534177, Type: Literature]
View
37
[SID104234256]
Antimicrobial activity against Escherichia coli TOP10 by Etest method [AID534178, Type: Literature]
View
38
[SID104234256]
Volume of distribution at steady state in human after iv administration [AID540209, Type: Literature]
View
39
[SID104234256]
Clearance in human after iv administration [AID540210, Type: Literature]
View
40
[SID104234256]
Fraction unbound in human after iv administration [AID540211, Type: Literature]
View
41
[SID104234256]
Mean residence time in human after iv administration [AID540212, Type: Literature]
View
42
[SID104234256]
Half life in human after iv administration [AID540213, Type: Literature]
View
43
[SID104234256]
IC50 DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) [AID625145, Type: other]Cysteinyl leukotriene receptor 1 [gi:20138087]
View
44
[SID104234256]
IC50 DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) [AID625203, Type: other]Alpha-2C adrenergic receptor [gi:20141211]
View
45
[SID104234256]
IC50 DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625154, Type: other]Muscarinic acetylcholine receptor M4 [gi:23503039]
View
46
[SID104234256]
IC50 DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) [AID625202, Type: other]Alpha-2B adrenergic receptor [gi:27151763]
View
47
[SID104234256]
DRUGMATRIX: Protein Tyrosine Phosphatase, PTPRC (CD45) enzyme inhibition (substrate: DiFMUP) [AID625188, Type: other]Receptor-type tyrosine-protein phosphatase C [gi:33112650]
View
48
[SID104234256]
IC50 DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) [AID625204, Type: other]Beta-1 adrenergic receptor [gi:48429211]
View
49
[SID104234256]
IC50 DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625148, Type: other]Melanocortin receptor 4 [gi:60392672]
View
50
[SID104234256]
IC50 DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625247, Type: other]Cytochrome P450 2C19 [gi:60416369]
View