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Saquinavir (CID 441243) - Compound BioActivity Data
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BioActivity Outcomes:
Active(320)
 
 
Inactive(519)
 
 
Inconclusive(25)
 
 
Unspecified(578)
 
 
Top Targets:
7tm 4(68)
 
 
 
 
ABC MTABC3 MD..(22)
 
 
p450(15)
 
 
 
HIV retropeps..(9)
 
 
CAP ED(7)
 
 
 
BioAssay Types:
Literature(661)
 
 
 
 
 
Screening(367)
 
 
 
Confirmatory(286)
 
 
 
 
 
BioActivity Types:
IC50(252)
 
 
 
 
EC50(117)
 
 
 
 
 
Potency(116)
 
 
 
 
 
Ki(48)
 
 
 
Kd(13)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1382    Data Row: 1442   Total Pages: 73   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179606]
Ki 4e-05Inhibition of wild-type HIV1 BH10 protease expressed in Escherichia coli by spectrophotometric assay [AID343014, Type: Literature]
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2
[SID103179606]
Ki 4e-05Inhibition of HIV protease [AID160300, Type: Literature]Pol polyprotein [gi:75593047]
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3
[SID103179606]
Ki 6.2e-05Dissociation constant obtained by inhibition of Wild-type protease [AID219260, Type: Literature]
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4
[SID103179606]
Ki 8e-05Inhibition of HIV1 protease [AID374591, Type: Literature]
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5
[SID103179606]
Ki 0.00012Binding activity against HIV-1 Protease [AID163470, Type: Literature]
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6
[SID103179606]
Ki 0.00012The compound was tested for binding activity against HIV-1 protease [AID163472, Type: Literature]
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7
[SID103179606]
Ki 0.00012Compound was tested for its inhibitory potency against human immunodeficiency virus -1 (HIV-1 protease); In house preparation [AID82624, Type: Literature]
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8
[SID46392170]
Ki 0.00012Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Hiv-1 Proteinase Complexed With Ro 31-8959 [gi:1942190]
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9
[SID46392170]
Ki 0.00012Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Hiv-1 Proteinase Complexed With Ro 31-8959 [gi:1942190]
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10
[SID46392170]
Ki 0.00012Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Hiv-1 Proteinase Complexed With Ro 31-8959 [gi:1942191]
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11
[SID46392170]
Ki 0.00012Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Hiv-1 Proteinase Complexed With Ro 31-8959 [gi:1942191]
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12
[SID103179606]
Ki 0.000138Inhibition of HIV1 protease [AID321660, Type: Literature]
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13
[SID103179606]
Ki 0.00019Inhibitory activity against HIV-1 protease [AID160477, Type: Literature]
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14
[SID103179606]
Ki 0.0002Inhibition of HIV1 protease expressed in Escherichia coli by fluorometric assay [AID443165, Type: Literature]
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15
[SID103179606]
EC50 0.0002Antiviral activity against HIV2 ROD with protease V47A mutation infected in human CEM cells assessed as inhibition of virus production after 7 days by Lenti-RT activity assay [AID369953, Type: Literature]
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16
[SID103179606]
EC50 0.0002Antiviral activity against HIV2 ROD with protease G17N/V47A mutation infected in human CEM cells assessed as inhibition of virus production after 7 days by Lenti-RT activity assay [AID369954, Type: Literature]
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17
[SID103179606]
IC50 0.0002In vitro inhibition HIV-1 IIIB protease. [AID82291, Type: confirmatory]
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18
[SID103179606]
Ki 0.00022Inhibition of HIV1 recombinant protease V32I/I47A mutant expressed in Escherichia coli by spectrophotometric assay [AID343018, Type: Literature]
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19
[SID103179606]
IC50 0.000229Inhibition of HIV-1 protease was determined in vitro [AID160772, Type: Literature]
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20
[SID103179606]
IC50 0.000229Inhibitory activity against HIV-1 protease. [AID160770, Type: Literature]Pol polyprotein [gi:75593047]
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