Bookmark and Share
Captopril (CID 44093) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(98)
 
 
Inactive(1362)
 
 
Inconclusive(82)
 
 
Unspecified(1654)
 
 
Top Targets:
7TM GPCR Srx(49)
 
 
 
7TM GPCR Srsx(39)
 
 
 
 
M2 ACE(38)
 
 
 
Tryp SPc(17)
 
 
 
p450(15)
 
 
 
BioAssay Types:
Confirmatory(737)
 
 
 
 
 
Screening(635)
 
 
 
 
Literature(430)
 
 
 
 
 
Summary(25)
 
 
 
BioActivity Types:
Potency(527)
 
 
 
 
 
IC50(251)
 
 
 
 
 
Ki(14)
 
 
 
EC50(11)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2827    Data Row: 3196   Total Pages: 160   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103581295]
IC50 2.7e-08In vitro inhibitory activity against Angiotensin I converting enzyme [AID37667, Type: Literature]Angiotensin-converting enzyme [gi:2822103]
View
2
[SID103581295]
IC50 0.00012Inhibition of human recombinant ACE by fluorimetry [AID433785, Type: Literature]Angiotensin-converting enzyme [gi:113045]
View
3
[SID103581295]
IC50 0.00063Inhibition of human ACE [AID340316, Type: Literature]Angiotensin-converting enzyme [gi:113045]
View
4
[SID46392259]
Ki 0.0011Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Drosophila Ance [gi:34811336]
View
5
[SID46392259]
Ki 0.0011Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Drosophila Ance [gi:34811336]
View
6
[SID103581295]
Ki 0.0017Antihypertensive activity against human renin [AID198995, Type: Literature]Renin [gi:132326]
View
7
[SID103581295]
Ki 0.0017Inhibitory activity against rabbit lung angiotensin-1 converting enzyme [AID37801, Type: Literature]Angiotensin-converting enzyme [gi:2822103]
View
8
[SID103581295]
Ki 0.002Inhibition of Angiotensin I converting enzyme (ACE) [AID38253, Type: Literature]
View
9
[SID103581295]
IC50 0.0023In vitro inhibitory activity was evaluated against angiotensin converting enzyme from rabbit in bovine buffered base. (reported from ref. 1b) [AID38438, Type: confirmatory]Angiotensin-converting enzyme [gi:2822103]
View
10
[SID103581295]
IC50 0.003In vitro inhibitory activity against rat serum angiotensin I converting enzyme using hippuryl-glycyl-glycine as substrate [AID39615, Type: Literature]
View
11
[SID103581295]
IC50 0.0036In vitro inhibitory activity was evaluated against angiotensin converting enzyme from rabbit in bovine buffered base [AID38437, Type: confirmatory]Angiotensin-converting enzyme [gi:2822103]
View
12
[SID103581295]
IC50 0.005Inhibition of ACE by fluorometric assay [AID338980, Type: Literature]
View
13
[SID103581295]
IC50 0.0077Inhibition of ACE [AID319059, Type: Literature]
View
14
[SID103581295]
IC50 0.009Inhibition of guinea pig serum Angiotensin I converting enzyme [AID39752, Type: Literature]
View
15
[SID103581295]
IC50 0.009Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50% [AID39754, Type: Literature]
View
16
[SID103581295]
IC50 0.01In vitro inhibitory concentration against angiotensin-converting enzyme [AID38458, Type: confirmatory]
View
17
[SID103581295]
IC50 0.01Evaluation of in vitro inhibitory activity against Angiotensin I converting enzyme [AID37656, Type: Literature]
View
18
[SID103581295]
IC50 0.011In vitro inhibitory activity against Angiotensin I converting enzyme [AID38092, Type: Literature]
View
19
[SID103581295]
IC50 0.012Concentration required for 50% inhibition of Angiotensin I converting enzyme [AID39755, Type: Literature]
View
20
[SID103581295]
IC50 0.012Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate. [AID38089, Type: Literature]
View