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taxifolin (CID 439533) - Compound BioActivity Data
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BioActivity Outcomes:
Active(21)
 
 
Inactive(589)
 
 
Inconclusive(17)
 
 
Unspecified(55)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(17)
 
 
Bcl-2 like(11)
 
 
G-alpha(7)
 
 
 
NR LBD PPAR(6)
 
 
BioAssay Types:
Screening(433)
 
 
 
 
Confirmatory(157)
 
 
 
 
 
Literature(66)
 
 
 
 
 
BioActivity Types:
Potency(128)
 
 
 
 
 
IC50(32)
 
 
 
 
 
EC50(9)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 614    Data Row: 682   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56463005]
Potency 0.5623qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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2
[SID26719897]
Potency 3.1623qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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3
[SID49681666]
IC50 5.9A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag - Counter Screen [AID2501, Type: confirmatory]
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4
[SID26719897]
Potency 10qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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5
[SID26719897]
Potency 19.9526qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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6
[SID103168531]
IC50 24.2Antioxidant activity assessed as superoxide radical anion scavenging activity [AID380203, Type: Literature]
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7
[SID49681666]
IC50 31.96Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents [AID1903, Type: confirmatory]large T antigen [Simian virus 40] [gi:297591903]
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8
[SID103168531]
IC50 35Inhibition of human Beta-secretase 1 [AID44249, Type: Literature]Beta-secretase 1 [gi:296434407]
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9
[SID103168531]
IC50 40.1Inhibition of reduced carboxymethylated kappa-casein fibril formation measured every 5 mins after 1000 mins by thioflavin T staining-based binding assay [AID456187, Type: Literature]
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10
[SID103168531]
EC50 45Anti-HIV activity in cell culture assay expressed as EC50 values. [AID81248, Type: confirmatory]
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11
[SID103168531]
IC50 45Anti-HIV activity in cell culture assay expressed as IC50 values. [AID81601, Type: confirmatory]
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12
[SID56463005]
Potency 79.4328qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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13
[SID49681666]
uHTS Luminescent assay for identification of inhibitors of mouse intestinal alkaline phosphatase [AID2806, Type: screening]intestinal alkaline phosphatase precursor [Mus musculus] [gi:124487323]
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14
[SID49681666]
Single concentration confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay [AID434971, Type: screening]intestinal alkaline phosphatase precursor [Mus musculus] [gi:124487323]
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15
[SID26719897]
QFRET-based primary biochemical high throughput screening assay to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). [AID1822, Type: screening]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23505220]
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16
[SID56463005]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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17
[SID49681666]
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS [AID485317, Type: screening]FAD-linked sulfhydryl oxidase ALR [Homo sapiens] [gi:54112432]
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18
[SID103168531]
Antioxidant activity assessed as DPPH radical scavenging activity after 20 min [AID293297, Type: Literature]
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19
[SID103168531]
IC50 Antioxidant activity assessed as inhibition of superoxide production by xanthine/xanthine oxidase method [AID293298, Type: Literature]
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20
[SID56463005]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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