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1-(2,5-dimethyl-1-prop-2-enylpyrrol-3-yl)-2-(6-methyl-2-nitropyridin-3-yl)oxyethanone (CID 4354817) - Compound BioActivity Data
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BioActivity Outcomes:
Active(29)
 
 
Inactive(675)
 
 
Inconclusive(27)
 
 
Unspecified(8)
 
 
Top Targets:
7tm 4(44)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
PP1c bdg(9)
 
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(487)
 
 
 
 
 
Confirmatory(226)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(151)
 
 
 
 
 
IC50(61)
 
 
 
 
 
EC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 660    Data Row: 739   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID22409458]
Potency 0.46qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. [AID588397, Type: confirmatory]
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2
[SID22409458]
IC50 0.946Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID624395, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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3
[SID22409458]
IC50_1_PEG-3 24hr 3.376Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_4, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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4
[SID22409458]
Potency 3.9811qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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5
[SID22409458]
IC50 4.694Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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6
[SID22409458]
IC50 5.779HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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7
[SID22409458]
EC50 6.96uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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8
[SID22409458]
IC50_1_GAPDH 6hr 8.439Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_1, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
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9
[SID22409458]
IC50_1_PEG-3 6hr 9.648Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_3, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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10
[SID22409458]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID22409458]
HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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12
[SID22409458]
Single concentration confirmation of uHTS hits for Peg3 Promoter Inhibitors via a luciferase reporter assay [AID602417, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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13
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_4, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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14
[SID22409458]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). [AID2098, Type: screening]Hsf1 protein [Mus musculus] [gi:62740231]
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15
[SID22409458]
uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
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16
[SID22409458]
Single concentration confirmation of uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID651580, Type: screening]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
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17
[SID22409458]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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18
[SID22409458]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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19
[SID22409458]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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20
[SID22409458]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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