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AC1N94DM (CID 4354817) - Compound BioActivity Data
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BioActivity Outcomes:
Active(29)
 
 
Inactive(667)
 
 
Inconclusive(27)
 
 
Unspecified(8)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(20)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
PP1c bdg(9)
 
 
 
 
BioAssay Types:
Screening(485)
 
 
 
 
 
Confirmatory(226)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(151)
 
 
 
 
 
IC50(61)
 
 
 
 
 
EC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 658    Data Row: 731   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID22409458]
Potency 0.46qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. [AID588397, Type: confirmatory]
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2
[SID22409458]
IC50 0.946Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID624395, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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3
[SID22409458]
IC50_1_PEG-3 24hr 3.376Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_4, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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4
[SID22409458]
Potency 3.9811qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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5
[SID22409458]
IC50 4.694Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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6
[SID22409458]
IC50 5.779HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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7
[SID22409458]
EC50 6.96uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
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8
[SID22409458]
IC50_1_GAPDH 6hr 8.439Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_1, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
View
9
[SID22409458]
IC50_1_PEG-3 6hr 9.648Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_3, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
10
[SID22409458]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
11
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_4, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
12
[SID22409458]
HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
13
[SID22409458]
Single concentration confirmation of uHTS hits for Peg3 Promoter Inhibitors via a luciferase reporter assay [AID602417, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
14
[SID22409458]
Primary cell-based high throughput screening assay to measure STAT3 inhibition [AID862, Type: screening]STAT3 [Homo sapiens] [gi:13272532]
View
15
[SID22409458]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
16
[SID22409458]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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17
[SID22409458]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
18
[SID22409458]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
19
[SID22409458]
uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
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20
[SID22409458]
Single concentration confirmation of uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID651580, Type: screening]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
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21
[SID22409458]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). [AID2098, Type: screening]Hsf1 protein [Mus musculus] [gi:62740231]
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22
[SID22409458]
Full deck counterscreen for agonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602248, Type: screening]
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23
[SID22409458]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]COUP transcription factor 2 isoform a [Homo sapiens] [gi:14149746]
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24
[SID22409458]
Single concentration confirmation of HIF-2a Inhibitors in a HIF-1a counterscreen in human MiAPaCa-2 Cells luciferase reporter assay [AID651589, Type: screening]hypoxia-inducible factor 1-alpha isoform 1 [Homo sapiens] [gi:4504385]
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25
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_1, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
View
26
[SID22409458]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2) [AID651957, Type: screening]nuclear receptor coactivator 2 [Homo sapiens] [gi:5729858]
View
27
[SID22409458]
Luminescence-based cell-based high throughput confirmation assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2) [AID652008, Type: screening]nuclear receptor coactivator 2 [Homo sapiens] [gi:5729858]
View
28
[SID22409458]
Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID602229, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
29
[SID22409458]
Luminescence-based cell-based high throughput confirmation assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624378, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
30
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_2, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
View
31
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_3, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
View
32
[SID22409458]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
33
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_8, Type: confirmatory]
View
34
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_9, Type: confirmatory]
View
35
[SID22409458]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
36
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_5, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
37
[SID22409458]
IC50_PEG-3_Mean Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167_6, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
38
[SID22409458]
IC50_PEG-3_Mean 1.4Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in a screening assay [AID624167, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
39
[SID22409458]
Potency 11.2202qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
40
[SID22409458]
IC50 14.175Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID602167, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
41
[SID22409458]
Potency 18.526Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
42
[SID22409458]
IC50 20uHTS Fluorescence assay for the identification of cytotoxic compounds among compounds active in NOD2 cell inhibition assay [AID1848, Type: confirmatory]
View
43
[SID22409458]
IC50 20uHTS Fluorescence assay for the identification of cytotoxic compounds among compounds active in NOD1 cell inhibition assay [AID1849, Type: confirmatory]
View
44
[SID22409458]
EC50 20uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
45
[SID22409458]
IC50 20uHTS luminescence assay for the identification of compounds that inhibit NOD2 in MDP treated cells [AID2001, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
46
[SID22409458]
Potency 22.3872qHTS of PTHR Inhibitors: Primary Screen [AID743266, Type: confirmatory]parathyroid hormone/parathyroid hormone-related peptide receptor precursor [Homo sapiens] [gi:296080761]
View
47
[SID22409458]
IC50 35.875Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1) [AID602168, Type: confirmatory]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
View
48
[SID22409458]
IC50 35.875Luminescence-based cell-based high throughput dose response assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID602166, Type: confirmatory]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
View
49
[SID22409458]
IC50_1_GAPDH 24hr 36.184Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_2, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
View
50
[SID22409458]
Potency 89.1251qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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