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BioActivity Data for Compound F1808-0172 (CID 4289057)

BioActivity Outcomes:
Probe(1)
 
 
Active(35)
 
 
Inactive(803)
 
 
Inconclusive(26)
 
 
Unspecified(9)
 
 
Top Targets:
7tm 4(48)
 
 
alkPPc(14)
 
 
PTPc(13)
 
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
 
BioAssay Types:
Screening(575)
 
 
 
 
 
Confirmatory(271)
 
 
 
 
 
Literature(14)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(172)
 
 
 
 
 
IC50(70)
 
 
 
 
EC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 793    Data Row: 874   Total Pages: 44   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7970631]
Summary of probe development efforts to identify inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1). [AID1844, Type: summary]steroidogenic factor-1 [Homo sapiens] [gi:216409744]
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2
[SID103565234]
IC50 0.26Inhibition of GAL4-tagged NR5A1 by luciferase assay [AID329653, Type: Literature]
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3
[SID7970631]
IC50_Mean 2.23Dose response counterscreen of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay [AID489041, Type: confirmatory]
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4
[SID7970631]
Potency 2.3109qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID7970631]
Potency 2.5929qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID7970631]
Potency 4.1095A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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7
[SID56373597]
IC50 4.9336Confirmation of image-based Screening Assay for Inhibitors of Phagocytosis [AID1618, Type: confirmatory]
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8
[SID7970631]
Potency 6.5131A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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9
[SID7970631]
IC50_Mean 9.88Dose response confirmation of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a Jurkat cell line using a luminescence assay [AID489035, Type: confirmatory]
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10
[SID56373597]
IC50_Mean 11.4SAR analysis of compounds that inhibit HePTP - Set 2 [AID449736, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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11
[SID7970631]
Potency 20.5962qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling: Hit Validation in Primary Screen [AID651558, Type: confirmatory]
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12
[SID7970631]
Potency 100qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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13
[SID56436611]
Counterscreen for agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based full-deck high throughput screening assay to identify agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A) [AID504692, Type: screening]5-hydroxytryptamine receptor 5A [Homo sapiens] [gi:13236497]
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14
[SID7970631]
Primary Cell-based High Throughput Screening assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) [AID525, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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15
[SID7970631]
Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) [AID600, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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16
[SID7970631]
HCS assay for microtubule stabilizers [AID2205, Type: screening]tubulin beta chain isoform b [Homo sapiens] [gi:29788785]
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17
[SID7970631]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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18
[SID7970631]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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19
[SID7970631]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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20
[SID7970631]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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