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Idarubicin (CID 42890) - Compound BioActivity Data
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BioActivity Outcomes:
Active(148)
 
 
Inactive(89)
 
 
Inconclusive(56)
 
 
Unspecified(342)
 
 
Top Targets:
7TM GPCR Srx(22)
 
 
 
 
 
7TM GPCR Srsx(16)
 
 
 
p450(8)
 
 
HELICc(7)
 
 
 
Bromo ALL-1(6)
 
 
BioAssay Types:
Confirmatory(300)
 
 
 
 
 
Literature(124)
 
 
 
 
 
Screening(13)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(177)
 
 
 
 
IC50(143)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 544    Data Row: 635   Total Pages: 32   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103311042]
IC50 0.00071Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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2
[SID103311042]
IC50 0.001Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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3
[SID103311042]
IC50 0.00105Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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4
[SID103311042]
IC50 0.00105Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
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5
[SID103311042]
IC50 0.00117Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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6
[SID103311042]
IC50 0.00126Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
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7
[SID103311042]
IC50 0.00141Antiplasmodial activity against Plasmodium falciparum Dd2 after 72 hrs by SYBR green assay [AID524793, Type: Literature]
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8
[SID103311042]
IC50 0.002Cytotoxic activity against K562 erythroleukemic cells [AID95000, Type: Literature]
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9
[SID103311042]
IC50 0.012Cytotoxicity against human K562 cells after 5 days by XTT assay [AID312292, Type: Literature]
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10
[SID50106402]
Potency 0.0398qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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11
[SID50106403]
Potency 0.0398qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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12
[SID50106404]
Potency 0.0398qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
View
13
[SID50106404]
Potency 0.0999S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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14
[SID90340569]
Potency 0.4108qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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15
[SID90340569]
Potency 0.414High Content Imaging Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF Cells [AID2667, Type: confirmatory]serine/threonine-protein kinase mTOR [Homo sapiens] [gi:4826730]
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16
[SID50106402]
Potency 0.5623Counterscreen for RECQ1 Inhibitors: ADP Fluorescence Polarization Displacement Assay [AID2711, Type: confirmatory]
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17
[SID50106402]
Potency 0.5623Counterscreen for BLMA Inhibitors: ADP Fluorescence Polarization Displacement Assay [AID2712, Type: confirmatory]
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18
[SID90340569]
Potency 0.5802Validation screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID493106, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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19
[SID50106404]
Potency 0.631qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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20
[SID103311042]
IC50 0.7Inhibition of NDM-1 (unknown origin) using nitrocefin as substrate preincubated 10 mins followed by substrate addition measured after 20 mins [AID749000, Type: Literature]
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