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BioActivity Data for Compound DEET (CID 4284)

BioActivity Outcomes:
Active(12)
 
 
Inactive(1096)
 
 
Inconclusive(62)
 
 
Unspecified(94)
 
 
Top Targets:
7tm 4(37)
 
 
NR LBD PPAR(34)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD AR(25)
 
 
 
NR LBD TR(19)
 
 
 
BioAssay Types:
Confirmatory(584)
 
 
 
 
 
Screening(359)
 
 
 
Literature(158)
 
 
 
 
 
Summary(87)
 
 
 
 
BioAssay Categories:
In vitro(3)
 
 
 
In vivo(3)
 
 
 
Biochemical(107)
 
 
Toxicity(73)
 
 
 
 
 
ADME(6)
 
 
Cell-based(126)
 
 
 
 
Organism-base..(14)
 
 
 
BioActivity Types:
Potency(596)
 
 
 
 
 
IC50(11)
 
 
AC50(6)
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 859    Data Row: 1264   Total Pages: 64   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144204654]
Potency-Replicate_1 2.6603qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144204654]
Potency-Replicate_1 21.3138qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID26747323]
Potency 25.1189qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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4
[SID144204654]
Ratio Potency (uM) 25.797qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID170483384]
Kd 31.3Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Odorant Binding Protein 1 From Anopheles Gambiae (Agamobp1) With Deet (N,N-Diethyl-Meta-Toluamide) And Peg [gi:335892259]
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6
[SID170483384]
Kd 31.3Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Odorant Binding Protein 1 From Anopheles Gambiae (Agamobp1) With Deet (N,N-Diethyl-Meta-Toluamide) And Peg [gi:335892259]
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7
[SID170483384]
Kd 31.3Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Crystal Structure Of Odorant Binding Protein 1 From Anopheles Gambiae (Agamobp1) With Deet (N,N-Diethyl-Meta-Toluamide) And Peg [gi:335892260]
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8
[SID170483384]
Kd 31.3Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Crystal Structure Of Odorant Binding Protein 1 From Anopheles Gambiae (Agamobp1) With Deet (N,N-Diethyl-Meta-Toluamide) And Peg [gi:335892260]
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9
[SID144209178]
Potency-Replicate_1 60.5094qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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10
[SID124958332]
Acaricidal activity against Dermatophagoides pteronyssinus assessed as mortality at 38.2 to 50.9 ug/cm2 after 24 to 72 hr by fabric disk assay relative to untreated control [AID1102056, Type: Literature]
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11
[SID48415187]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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12
[SID56320635]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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13
[SID26747323]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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14
[SID124958332]
Oviposition deterrent activity against adult female Trichoplusia ni (cabbage looper) moths introduced along with male moths into oviposition cage containing compound pretreated cabbage leaves assessed as eggs laying on the leaf disks at 0.25% after 48 hr [AID1104346, Type: Literature]
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15
[SID8150108]
Screen for compounds that induce the human heat shock transcriptional response (HSEluc) [AID1611, Type: other]
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16
[SID124958332]
Insecticidal activity against adult Tribolium castaneum (red flour beetle) assessed as repellent activity at 0.16 nL/cm2 after 4 hr [AID1082375, Type: Literature]
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17
[SID8150108]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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18
[SID8150108]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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19
[SID8150108]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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20
[SID8150108]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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