Bookmark and Share
trimethylenediamine (CID 428) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(1)
 
 
Unspecified(19)
 
 
Top Targets:
PBP1 iGluR NM..(4)
 
 
PBP1 iGluR NM..(2)
 
 
PBP1 iGluR NM..(1)
 
 
BioAssay Types:
Literature(20)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 21   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48415098]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
View
2
[SID103436106]
Percentage of the diamine which is monoprotonated at pH 7.4 [AID15290, Type: Literature]
View
3
[SID103436106]
Calculated partition coefficient (clogP) [AID15721, Type: Literature]
View
4
[SID103436106]
Partition coefficient (logP) [AID22299, Type: Literature]
View
5
[SID103436106]
Dissociation constant (pK1) [AID25056, Type: Literature]
View
6
[SID103436106]
Dissociation constant (pK2) [AID25063, Type: Literature]
View
7
[SID103436106]
Percent [3H]MK-801 bound to N-methyl-D-aspartate glutamate receptor in the presence of 20 uM spermine assuming 100% in the absence of added diamine. [AID143007, Type: Literature]
View
8
[SID103436106]
Cytotoxicity against mouse J774 macrophage assessed as cell viability at 1 ug/mL after 48 hrs by MTT assay [AID448381, Type: Literature]
View
9
[SID103436106]
Cytotoxicity against mouse J774 macrophage assessed as cell viability at 10 ug/mL after 48 hrs by MTT assay [AID448530, Type: Literature]
View
10
[SID103436106]
Cytotoxicity against mouse J774 macrophage assessed as cell viability at 100 ug/mL after 48 hrs by MTT assay [AID448531, Type: Literature]
View
11
[SID103436106]
Cytotoxicity against Mycobacterium bovis Bacillus Calmette-Guerin infected mouse J774 macrophage assessed as cell viability at 1 ug/mL after 48 hrs by MTT assay [AID448532, Type: Literature]
View
12
[SID103436106]
Cytotoxicity against Mycobacterium bovis Bacillus Calmette-Guerin infected mouse J774 macrophage assessed as cell viability at 10 ug/mL after 48 hrs by MTT assay [AID448533, Type: Literature]
View
13
[SID103436106]
Cytotoxicity against Mycobacterium bovis Bacillus Calmette-Guerin infected mouse J774 macrophage assessed as cell viability at 100 ug/mL after 48 hrs by MTT assay [AID448534, Type: Literature]
View
14
[SID103436106]
Enhanced binding of [3H]MK-801 to N-methyl-D-aspartate glutamate receptor in presence of spermine [AID143006, Type: Literature]Glutamate receptor ionotropic, NMDA 2B [gi:548372]
View
15
[SID103436106]
Enhanced binding of [3H]MK-801 to N-methyl-D-aspartate glutamate receptor in presence of spermine [AID143006, Type: Literature]Glutamate receptor ionotropic, NMDA 2C [gi:548374]
View
16
[SID103436106]
Enhanced binding of [3H]MK-801 to N-methyl-D-aspartate glutamate receptor in presence of spermine [AID143006, Type: Literature]Glutamate receptor ionotropic, NMDA 1 [gi:548379]
View
17
[SID103436106]
Enhanced binding of [3H]MK-801 to N-methyl-D-aspartate glutamate receptor in presence of spermine [AID143006, Type: Literature]Glutamate receptor ionotropic, NMDA 2A [gi:3915771]
View
18
[SID103436106]
Enhanced binding of [3H]MK-801 to N-methyl-D-aspartate glutamate receptor in presence of spermine [AID143006, Type: Literature]Glutamate receptor ionotropic, NMDA 2D [gi:18202594]
View
19
[SID103436106]
Enhanced binding of [3H]MK-801 to N-methyl-D-aspartate glutamate receptor in presence of spermine [AID143006, Type: Literature]Glutamate receptor ionotropic, NMDA 3B [gi:51701630]
View
20
[SID103436106]
Enhanced binding of [3H]MK-801 to N-methyl-D-aspartate glutamate receptor in presence of spermine [AID143006, Type: Literature]Glutamate receptor ionotropic, NMDA 3A [gi:51701631]
View
21
[SID103436106]
Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as minimum inhibitory concentration after 24 hrs by micro plate Alamar blue assay [AID448380, Type: Literature]
View