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ST081896 (CID 4274895) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(802)
 
 
Inconclusive(17)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(21)
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
 
BioAssay Types:
Screening(554)
 
 
 
 
Confirmatory(250)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(167)
 
 
 
 
 
IC50(50)
 
 
 
EC50(11)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 760    Data Row: 831   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7966860]
Potency 2.5929qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID7966860]
Potency 2.9093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID7966860]
Potency 11.5821qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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4
[SID7966860]
Potency 11.5821qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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5
[SID7966860]
Potency 12.9953A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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6
[SID7966860]
Dose-response cell-based assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID681, Type: confirmatory]Nuclear receptor ROR-alpha [gi:548814]
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7
[SID7966860]
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
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8
[SID7966860]
Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
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9
[SID7966860]
Cell Proliferation & Viability (Cytotoxicity) Dose Response Assay 60K MLSMR [AID464, Type: confirmatory]
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10
[SID7966860]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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11
[SID7966860]
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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12
[SID7966860]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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13
[SID7966860]
Factor XIa 1536 HTS [AID798, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
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14
[SID7966860]
Factor XIa Mixture HTS [AID680, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
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15
[SID7966860]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
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16
[SID7966860]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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17
[SID7966860]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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18
[SID7966860]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2. [AID950, Type: screening]Apoptosis regulator Bcl-2 [gi:231632]
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19
[SID7966860]
Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
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20
[SID7966860]
Primary screen for compounds that inhibit Alzheimer's amyloid precursor protein (APP) translation [AID1285, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
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