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SMR000207919 (CID 4230279) - Compound BioActivity Data
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BioActivity Outcomes:
Active(35)
 
 
Inactive(670)
 
 
Inconclusive(20)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(20)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(469)
 
 
 
 
Confirmatory(223)
 
 
 
 
 
Literature(14)
 
 
 
BioActivity Types:
Potency(158)
 
 
 
 
 
IC50(39)
 
 
 
 
EC50(11)
 
 
 
AC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 661    Data Row: 726   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17512507]
AC50_uM 0.009Turbidometric Biochemical Primary HTS to identify inhibitors of Protein Disulfide Isomerase Measured in Biochemical System Using Plate Reader - 2137-01_Inhibitor_Dose_CherryPick_Activity [AID602350, Type: confirmatory]Prolyl 4-hydroxylase, beta polypeptide [Homo sapiens] [gi:14790033]
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2
[SID17512507]
AC50_uM 0.009Turbidometric Biochemical Primary HTS to identify inhibitors of Protein Disulfide Isomerase Measured in Biochemical System Using Plate Reader - 2137-01_Inhibitor_Dose_CherryPick_Activity_Set2 [AID624274, Type: confirmatory]Prolyl 4-hydroxylase, beta polypeptide [Homo sapiens] [gi:14790033]
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3
[SID17512507]
Potency 2.8184qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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4
[SID17512507]
AC50_uM 2.89C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity [AID504725, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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5
[SID17512507]
Potency 2.9935qHTS Assay for the Inhibitors of L3MBTL1: Hit Validation [AID540279, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
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6
[SID17512507]
Potency 3.9716qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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7
[SID87342225]
AC50_uM 7.35Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_Dose_CherryPick_Activity [AID1053173, Type: confirmatory]histone-lysine N-methyltransferase NSD2 isoform 1 [Homo sapiens] [gi:109633019]
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8
[SID17512507]
Potency 7.5193qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds [AID720501, Type: Literature]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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9
[SID17512507]
Potency 7.9433qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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10
[SID17512507]
Potency 10qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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11
[SID17512507]
IC50 12.83Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) [AID1619, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:124809582]
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12
[SID17512507]
Potency 16.9441qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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13
[SID17512507]
AC50_uM 23.837C-LANA Counter Screen: DNA intercalators Measured in Biochemical System Using Plate Reader - 2117-02_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504727, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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14
[SID17512507]
Potency 31.6228qHTS Assay for the Inhibitors of L3MBTL1 [AID485360, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
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15
[SID17512507]
Potency 39.8107qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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16
[SID124360090]
AC50_uM 55.79C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_DryPowder_Activity [AID588363, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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17
[SID17512507]
EC50 61.638Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 [AID1960, Type: confirmatory]Zinc finger protein mex-5 [gi:55976631]
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18
[SID17512507]
Potency 79.4328qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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19
[SID17512507]
EC50 270.475Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA [AID1964, Type: confirmatory]Protein POS-1 [Caenorhabditis elegans] [gi:17562800]
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20
[SID17512507]
Luminescence-based biochemical primary high throughput screening assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID624268, Type: screening]methionyl-tRNA synthetase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:71746704]
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