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nitazoxanide (CID 41684) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(282)
 
 
Inactive(608)
 
 
Inconclusive(171)
 
 
Unspecified(198)
 
 
Top Targets:
NR LBD PPAR(27)
 
 
 
7tm 4(19)
 
 
 
NR LBD ER(16)
 
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD TR(12)
 
 
 
 
BioAssay Types:
Confirmatory(478)
 
 
 
 
Literature(344)
 
 
 
 
 
Screening(200)
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(368)
 
 
 
 
IC50(54)
 
 
 
 
EC50(17)
 
 
 
Ki(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 883    Data Row: 1259   Total Pages: 63   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103479736]
IC50 0.068Antiprotozoan activity against Trichomonas vaginalis GT3 trophozoites after 48 hrs [AID598282, Type: Literature]
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2
[SID103479736]
IC50 0.07943Antimicrobial activity against Trichomonas vaginalis GT3 incubated for 48 hrs followed by compound washout measured after 48 hrs [AID1067349, Type: Literature]
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3
[SID103479736]
EC50 0.12Antiviral activity against Hepatitis B virus infected in human HepG2(2.2.15) cells assessed as decrease in extracellular viral DNA measured 24 hrs after last dose [AID606883, Type: Literature]
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4
[SID103479736]
EC50 0.13Antiviral activity against HCV genotype 1a in replicon system [AID533311, Type: Literature]
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5
[SID103479736]
EC50 0.16Antiviral activity against HCV genotype 1b in RP7 replicon cell after 4 days by blot hybridization analysis [AID533313, Type: Literature]
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6
[SID103479736]
EC50 0.21Antiviral activity against HCV genotype 1b infected in Ava5 cells assessed as inhibition of viral replication after 3 days by blot hybridization analysis [AID642456, Type: Literature]
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7
[SID103479736]
Ki 0.3Inhibition of Giardia lamblia recombinant nitroreductase 1 (EAA43030.1) expressed in Escherichia coli [AID325504, Type: Literature]
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8
[SID103479736]
EC50 0.33Antiviral activity against HCV genotype 1a infected in Huh7.5 cells assessed as inhibition of viral replication after 3 days by blot hybridization analysis [AID642459, Type: Literature]
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9
[SID144208424]
Potency-Replicate_1 0.3507qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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10
[SID26719875]
Potency 0.5012qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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11
[SID103479736]
IC50 0.504Antiprotozoan activity against Entamoeba histolytica HM1-IMSS trophozoites after 48 hrs [AID598283, Type: Literature]
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12
[SID144208424]
Ratio Potency (uM) 0.555791qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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13
[SID144208424]
Potency-Replicate_1 0.5558qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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14
[SID103479736]
EC50 0.59Antiviral activity against Hepatitis B virus infected in human HepG2(2.2.15) cells assessed as decrease in intracellular viral DNA measured 24 hrs after last dose [AID606884, Type: Literature]
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15
[SID144204569]
Potency-Replicate_1 0.6682qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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16
[SID17388853]
Potency 0.7079qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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17
[SID17388853]
Potency 0.7208Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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18
[SID170465090]
Potency-Replicate_1 1.1882qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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19
[SID144204569]
ATAD5 Potency (uM) 1.18832qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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20
[SID103479736]
EC50 1.2Antiviral activity against HCV genotype 1b in NTZ-11 replicon cell after 4 days by blot hybridization analysis [AID533314, Type: Literature]
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