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(+)-|A-methyldopa (CID 4138) - Compound BioActivity Data
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BioActivity Outcomes:
Active(20)
 
 
Inactive(119)
 
 
Inconclusive(28)
 
 
Unspecified(3)
 
 
Top Targets:
Pyr redox dim(5)
 
 
 
 
7TM GPCR Srx(5)
 
 
 
HELICc(4)
 
 
 
 
PIKKc TOR(4)
 
 
SIS(3)
 
 
BioAssay Types:
Confirmatory(139)
 
 
 
 
 
Screening(13)
 
 
 
Literature(8)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(139)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 151    Data Row: 170   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50106598]
Potency 0.7943qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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2
[SID90340754]
Potency 0.9466qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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3
[SID50106598]
Potency 1.122qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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4
[SID50106598]
Potency 2.2387qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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5
[SID90340754]
Potency 2.3778qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails [AID488949, Type: confirmatory]M-phase phosphoprotein 8 [Homo sapiens] [gi:41055989]
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6
[SID90340754]
Potency 2.3778qHTS Validation Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1) [AID488816, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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7
[SID90340754]
Potency 2.3778qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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8
[SID90340754]
Potency 2.9935qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1) [AID488773, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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9
[SID50106598]
Potency 3.1623qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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10
[SID50106598]
Potency 3.5481qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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11
[SID50106598]
Potency 3.9811qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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12
[SID90340754]
Potency 5.3233qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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13
[SID50106598]
Potency 5.6234qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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14
[SID50106598]
Potency 10qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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15
[SID90340754]
Potency 10.6213Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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16
[SID85231121]
Potency 79.4328qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails [AID488949, Type: confirmatory]M-phase phosphoprotein 8 [Homo sapiens] [gi:41055989]
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17
[SID17405331]
HTS of LOPAC library for Estrogen Receptor-alpha Coactivator Binding inhibitors [AID694, Type: confirmatory]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
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18
[SID17405331]
HTS for Tumor Hsp90 Inhibitors [AID429, Type: screening]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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19
[SID17405331]
HTS for Tumor Hsp90 Inhibitors [AID429, Type: screening]90-kda heat shock protein beta HSP90 beta [Homo sapiens] [gi:4261762]
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20
[SID85209727]
Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
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