Bookmark and Share
CHEMBL262079 (CID 4131581) - Compound BioActivity Data
.
BioActivity Outcomes:
Probe(1)
 
 
Active(5)
 
 
Inactive(193)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srsx(10)
 
 
7TM GPCR Srx(7)
 
 
RasGEF(4)
 
 
NR DBD CAR(3)
 
 
Anthrax-tox M(3)
 
 
BioAssay Types:
Screening(148)
 
 
 
Confirmatory(34)
 
 
Literature(15)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(34)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 187    Data Row: 201   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46499821]
Summary of probe development efforts to identify inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1). [AID1844, Type: summary]steroidogenic factor-1 [Homo sapiens] [gi:216409744]
View
2
[SID103565115]
IC50 0.2Inhibition of GAL4-tagged NR5A1 by luciferase assay [AID329653, Type: Literature]
View
3
[SID103565115]
IC50 0.2Inverse agonist activity at SF-1 [AID593523, Type: Literature]
View
4
[SID103565115]
Antiproliferative activity against SF-1 negative human SW13 cells [AID593524, Type: Literature]
View
5
[SID103565115]
Inhibition of doxycycline induced proliferation in human NCI-H295RR cells [AID593525, Type: Literature]
View
6
[SID99495561]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
View
7
[SID103565115]
Inhibition of GAL4-tagged RORalpha at 100 uM by luciferase assay [AID329656, Type: Literature]
View
8
[SID103565115]
Inhibition of HSV1 GAL4-tagged VP16 at 100 uM by luciferase assay [AID329658, Type: Literature]
View
9
[SID99495561]
uHTS identification of small molecule inhibitors of the mitochondrial permeability transition pore via an absorbance assay [AID602449, Type: screening]
View
10
[SID99495561]
Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Activator_SinglePoint_HTS_Activity [AID623901, Type: screening]
View
11
[SID99495561]
Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Absorbance-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) full deck assay to identify assay artifacts [AID588335, Type: screening]
View
12
[SID99495561]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
View
13
[SID99495561]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
View
14
[SID99495561]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
View
15
[SID99495561]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
View
16
[SID99495561]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
View
17
[SID99495561]
HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
View
18
[SID99495561]
Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
View
19
[SID99495561]
Flow Cytometric HTS Screening for Inhibitors of Lytic Granule Exocytosis with MLPCN Compound Library [AID651702, Type: screening]
View
20
[SID99495561]
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
View