Bookmark and Share
CHEMBL262079 (CID 4131581) - Compound BioActivity Data
.
BioActivity Outcomes:
Probe(1)
 
 
Active(5)
 
 
Inactive(193)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(17)
 
 
RasGEF(4)
 
 
Anthrax-tox M(3)
 
 
NR DBD CAR(3)
 
 
Toxin trans(3)
 
 
BioAssay Types:
Screening(148)
 
 
 
Confirmatory(34)
 
 
Literature(15)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(34)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 187    Data Row: 201   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46499821]
Summary of probe development efforts to identify inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1). [AID1844, Type: summary]steroidogenic factor-1 [Homo sapiens] [gi:216409744]
View
2
[SID103565115]
IC50 0.2Inhibition of GAL4-tagged NR5A1 by luciferase assay [AID329653, Type: Literature]
View
3
[SID103565115]
IC50 0.2Inverse agonist activity at SF-1 [AID593523, Type: Literature]
View
4
[SID103565115]
Antiproliferative activity against SF-1 negative human SW13 cells [AID593524, Type: Literature]
View
5
[SID103565115]
Inhibition of doxycycline induced proliferation in human NCI-H295RR cells [AID593525, Type: Literature]
View
6
[SID99495561]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
View
7
[SID103565115]
Inhibition of GAL4-tagged RORalpha at 100 uM by luciferase assay [AID329656, Type: Literature]
View
8
[SID103565115]
Inhibition of HSV1 GAL4-tagged VP16 at 100 uM by luciferase assay [AID329658, Type: Literature]
View
9
[SID99495561]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
View
10
[SID99495561]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
View
11
[SID99495561]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
View
12
[SID99495561]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
View
13
[SID99495561]
Potency qHTS of alpha-syn Inhibitors [AID652106, Type: confirmatory]Alpha-synuclein [gi:586067]
View
14
[SID99495561]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
View
15
[SID99495561]
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
View
16
[SID99495561]
qHTS Assay for Inhibitors of the Six1/Eya2 Interaction [AID651725, Type: screening]six1 [Homo sapiens] [gi:1246761]
View
17
[SID99495561]
Potency qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
View
18
[SID99495561]
uHTS identification of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay [AID651560, Type: screening]Low molecular weight phosphotyrosine protein phosphatase [gi:1709543]
View
19
[SID99495561]
Potency qHTS of GLP-1 Receptor Agonists [AID624172, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
View
20
[SID99495561]
Potency qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
View