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BioActivity Data for Compound CHEMBL262079 (CID 4131581)

BioActivity Outcomes:
Probe(1)
 
 
Active(5)
 
 
Inactive(193)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(17)
 
 
RasGEF(4)
 
 
NR DBD CAR(3)
 
 
Anthrax-tox M(3)
 
 
Toxin trans(3)
 
 
BioAssay Types:
Screening(148)
 
 
 
Confirmatory(34)
 
 
Literature(15)
 
 
 
 
Summary(1)
 
 
BioAssay Categories:
Organism-base..(5)
 
 
Biochemical(50)
 
 
 
 
Toxicity(2)
 
 
Cell-based(56)
 
 
 
BioActivity Types:
Potency(34)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 187    Data Row: 201   Total Pages: 11   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46499821]
Summary of probe development efforts to identify inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1). [AID1844, Type: summary]steroidogenic factor-1 [Homo sapiens] [gi:216409744]
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2
[SID103565115]
IC50 0.2Inhibition of GAL4-tagged NR5A1 by luciferase assay [AID329653, Type: Literature]
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3
[SID103565115]
IC50 0.2Inverse agonist activity at SF-1 [AID593523, Type: Literature]
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4
[SID103565115]
Inhibition of doxycycline induced proliferation in human NCI-H295RR cells [AID593525, Type: Literature]
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5
[SID103565115]
Antiproliferative activity against SF-1 negative human SW13 cells [AID593524, Type: Literature]
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6
[SID99495561]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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7
[SID103565115]
Inhibition of HSV1 GAL4-tagged VP16 at 100 uM by luciferase assay [AID329658, Type: Literature]
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8
[SID103565115]
Inhibition of GAL4-tagged RORalpha at 100 uM by luciferase assay [AID329656, Type: Literature]
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9
[SID99495561]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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10
[SID99495561]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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11
[SID99495561]
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
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12
[SID99495561]
Flow Cytometric HTS Screening for Inhibitors of Lytic Granule Exocytosis with MLPCN Compound Library [AID651702, Type: screening]
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13
[SID99495561]
Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition [AID720647, Type: screening]
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14
[SID99495561]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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15
[SID99495561]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
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16
[SID99495561]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
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17
[SID99495561]
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity [AID743397, Type: screening]
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18
[SID99495561]
Wnt/Beta-catenin HTS Measured in Cell-Based System Using Plate Reader - 2161-01_Activator_SinglePoint_HTS_Activity [AID743398, Type: screening]
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19
[SID99495561]
Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
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20
[SID99495561]
HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
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