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methylmercuric chloride (CID 409301) - Compound BioActivity Data
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BioActivity Outcomes:
Active(255)
 
 
Inactive(80)
 
 
Inconclusive(77)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD AR(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
 
Summary(24)
 
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(193)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 242    Data Row: 415   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389834]
Potency 0.631qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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2
[SID17389834]
Potency 0.631qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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3
[SID17389834]
Potency 0.7079VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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4
[SID17389834]
Potency 0.7079qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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5
[SID144209722]
Ratio Potency (uM) 0.836128qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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6
[SID144209722]
Potency-Replicate_1 0.8609qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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7
[SID17389834]
Potency 0.8913qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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8
[SID144209722]
Potency-Replicate_1 1.216qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID17389834]
Potency 1.5849Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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10
[SID17389834]
Potency 1.5849Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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11
[SID17389834]
Potency 1.9953Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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12
[SID17389834]
Potency 2.2387qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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13
[SID17389834]
Potency 2.5119Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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14
[SID17389834]
Potency 2.5119Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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15
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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16
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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17
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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18
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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19
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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20
[SID17389834]
Potency 3.1623qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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21
[SID17389834]
Potency 3.9811Cell Viability - LYMP2-011 [AID969, Type: confirmatory]
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22
[SID17389834]
Potency 3.9811Cell Viability - LYMP2-013 [AID970, Type: confirmatory]
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23
[SID17389834]
Potency 3.9811Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
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24
[SID17389834]
Potency 3.9811Cell Viability - LYMP2-016 [AID984, Type: confirmatory]
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25
[SID17389834]
Potency 3.9811Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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26
[SID17389834]
Potency 3.9811Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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27
[SID144209722]
Potency-Replicate_1 4.841qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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28
[SID17389834]
Potency 5.0119Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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29
[SID17389834]
Potency 5.0119Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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30
[SID17389834]
Potency 5.0119Cell Viability - LYMP2-009 [AID968, Type: confirmatory]
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31
[SID17389834]
Potency 5.0119Cell Viability - LYMP2-006 [AID978, Type: confirmatory]
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32
[SID17389834]
Potency 5.0119Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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33
[SID17389834]
Potency 5.0119Cell Viability - LYMP2-023 [AID975, Type: confirmatory]
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34
[SID17389834]
Potency 5.0119Cell Viability - LYMP2-026 [AID989, Type: confirmatory]
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35
[SID17389834]
Potency 6.6824qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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36
[SID144209722]
ATAD5 Potency (uM) 7.10556qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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37
[SID17389834]
Potency 7.9433Cell Viability - LYMP2-025 [AID976, Type: confirmatory]
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38
[SID17389834]
Potency 7.9433Cell Viability - LYMP2-002 [AID977, Type: confirmatory]
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39
[SID144209722]
Potency-Replicate_1 8.6086qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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40
[SID17389834]
Potency-Replicate_1 10.5909qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
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41
[SID17389834]
Potency 11.2202qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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42
[SID144209722]
Potency-Replicate_1 12.2727qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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43
[SID144209722]
Potency-Replicate_1 12.2727qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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44
[SID17389834]
Potency 12.5893MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Live Cells [AID955, Type: confirmatory]
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45
[SID144209722]
Potency-Replicate_1 13.7702qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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46
[SID17389834]
Potency 15.8489qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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47
[SID17389834]
Potency 15.8489qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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48
[SID144209722]
Potency-Replicate_1 19.2722qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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49
[SID144209722]
Potency-Replicate_1 19.4509qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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50
[SID17389834]
Potency 19.9526MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Live Cells [AID962, Type: confirmatory]
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