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BioActivity Data for Compound methylmercuric chloride (CID 409301)

BioActivity Outcomes:
Active(259)
 
 
Inactive(80)
 
 
Inconclusive(88)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD AR(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(222)
 
 
 
 
Summary(28)
 
 
 
 
Literature(2)
 
 
BioAssay Categories:
In vivo(1)
 
 
Toxicity(36)
 
 
 
 
 
BioActivity Types:
Potency(208)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 256    Data Row: 430   Total Pages: 22   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389834]
Potency 0.631qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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2
[SID17389834]
Potency 0.631qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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3
[SID17389834]
Potency 0.7079qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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4
[SID17389834]
Potency 0.7079VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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5
[SID144209722]
Ratio Potency (uM) 0.836128qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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6
[SID144209722]
Potency-Replicate_1 0.8609qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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7
[SID17389834]
Potency 0.8913qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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8
[SID144209722]
Potency-Replicate_1 1.216qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID17389834]
Potency 1.5849Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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10
[SID17389834]
Potency 1.5849Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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11
[SID17389834]
Potency 1.9953Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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12
[SID17389834]
Potency 2.2387qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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13
[SID17389834]
Potency 2.5119Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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14
[SID17389834]
Potency 2.5119Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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15
[SID144209722]
Ratio Potency (uM) 2.74751qHTS assay to identify small molecule agonists of the AP-1 signaling pathway: Summary [AID1159528, Type: summary]v-jun sarcoma virus 17 oncogene homolog (avian) [Homo sapiens] [gi:119627033]
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16
[SID144209722]
Potency-Replicate_1 3.0544qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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17
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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18
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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19
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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20
[SID17389834]
Potency 3.1623Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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