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BioActivity Data for Compound Mesoridazine (CID 4078)

BioActivity Outcomes:
Active(29)
 
 
Inactive(309)
 
 
Inconclusive(63)
 
 
Unspecified(38)
 
 
Top Targets:
NR LBD ER(14)
 
 
NR LBD AR(14)
 
 
 
NR LBD PPAR(10)
 
 
NR LBD TR(8)
 
 
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Confirmatory(245)
 
 
 
 
Literature(102)
 
 
 
 
 
Summary(42)
 
 
 
Screening(33)
 
 
 
BioAssay Categories:
In vitro(2)
 
 
 
In vivo(2)
 
 
 
Biochemical(10)
 
 
 
Toxicity(12)
 
 
 
 
ADME(30)
 
 
Cell-based(25)
 
 
 
BioActivity Types:
Potency(206)
 
 
 
 
AC50(9)
 
 
 
IC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 300    Data Row: 439   Total Pages: 22   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103301322]
IC50 0.31623Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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2
[SID103301322]
IC50 0.32Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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3
[SID103301322]
IC50 0.32359Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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4
[SID103301322]
IC50 0.32359Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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5
[SID103301322]
IC50 0.54954Inhibitory concentration against potassium channel HERG [AID243151, Type: Literature]
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6
[SID26756521]
Potency 1.5101Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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7
[SID26756521]
Potency 5.6234qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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8
[SID170465272]
AC50 (uM) 7.0795qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
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9
[SID170465272]
Ac50 7.94328qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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10
[SID170465272]
AC50 (uM) 7.9433qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
View
11
[SID144205571]
Potency 8.9125qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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12
[SID144205571]
Potency-Replicate_1 13.3332qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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13
[SID144205571]
Potency-Replicate_1 13.3332qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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14
[SID170465272]
Ac50 19.3145qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 4, ratio channel [AID1117308, Type: confirmatory]
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15
[SID170465272]
Potency-Replicate_1 29.8493qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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16
[SID144205571]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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17
[SID144205571]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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18
[SID144205571]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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19
[SID170465272]
GSK3B-pretreated HCT116 viability from Cell TiterGlo-screen [AID1117336, Type: screening]
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20
[SID170465272]
HCT116 viability from Cell TiterGlo-screen [AID1117342, Type: screening]
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