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Mesoridazine (CID 4078) - Compound BioActivity Data
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BioActivity Outcomes:
Active(24)
 
 
Inactive(285)
 
 
Inconclusive(61)
 
 
Unspecified(33)
 
 
Top Targets:
NR LBD ER(14)
 
 
NR LBD AR(14)
 
 
 
NR LBD PPAR(10)
 
 
 
NR LBD TR(8)
 
 
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Confirmatory(225)
 
 
 
 
Literature(99)
 
 
 
 
 
Summary(39)
 
 
 
Screening(25)
 
 
BioActivity Types:
Potency(192)
 
 
 
 
IC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 265    Data Row: 403   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103301322]
IC50 0.31623Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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2
[SID103301322]
IC50 0.32Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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3
[SID103301322]
IC50 0.32359Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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4
[SID103301322]
IC50 0.32359Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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5
[SID103301322]
IC50 0.54954Inhibitory concentration against potassium channel HERG [AID243151, Type: Literature]
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6
[SID26756521]
Potency 1.5101Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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7
[SID26756521]
Potency 5.6234qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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8
[SID144205571]
Potency 8.9125qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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9
[SID144205571]
Potency-Replicate_1 13.3332qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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10
[SID144205571]
Potency-Replicate_1 13.3332qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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11
[SID144203603]
Potency-Replicate_1 26.6032qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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12
[SID144203603]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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13
[SID144205571]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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14
[SID144205571]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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15
[SID144205571]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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16
[SID26756521]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_57, Type: Literature]
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17
[SID48416224]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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18
[SID85209561]
Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
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19
[SID26756521]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_53, Type: Literature]
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20
[SID26756521]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_55, Type: Literature]
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21
[SID26756521]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
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22
[SID26756521]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_45, Type: Literature]
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23
[SID447728]
NCI AIDS Antiviral Assay [AID179, Type: confirmatory]
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24
[SID26756521]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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25
[SID26756521]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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26
[SID103301322]
logD (measured by HPLC) (as log k') [AID23959, Type: Literature]
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27
[SID103301322]
logD (measured by HPLC) (as log k') [AID23960, Type: Literature]
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28
[SID103301322]
logD (measured by HPLC) (as log k') [AID23961, Type: Literature]
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29
[SID103301322]
logD (measured by HPLC) (as log k') [AID23963, Type: Literature]
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30
[SID103301322]
logD (measured by HPLC) (as log k') [AID23965, Type: Literature]
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31
[SID103301322]
logD (measured by HPLC) (as log k') [AID23968, Type: Literature]
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32
[SID103301322]
logD (measured by HPLC) (as log k') [AID23970, Type: Literature]
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33
[SID103301322]
logD (measured by HPLC) (as log k') [AID23971, Type: Literature]
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34
[SID103301322]
Partition coefficient (logD, measured by HPLC, log k') [AID23973, Type: Literature]
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35
[SID103301322]
Partition coefficient (logD) (HPLC) [AID26294, Type: Literature]
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36
[SID103301322]
Partition coefficient (logD) (HPLC) [AID26295, Type: Literature]
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37
[SID103301322]
Partition coefficient (logD7.4) [AID26296, Type: Literature]
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38
[SID103301322]
Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset [AID588208, Type: Literature]
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39
[SID103301322]
Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset [AID588220, Type: Literature]
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40
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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41
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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42
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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43
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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44
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests [AID625283, Type: Literature]
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45
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure [AID625284, Type: Literature]
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46
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis [AID625285, Type: Literature]
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47
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis [AID625286, Type: Literature]
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48
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly [AID625287, Type: Literature]
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49
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice [AID625288, Type: Literature]
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50
[SID103301322]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease [AID625289, Type: Literature]
View