Mesoridazine (CID 4078) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(16)
 
 
Inactive(160)
 
 
Inconclusive(40)
 
 
Unspecified(33)
 
 
Top Targets:
CAP ED(5)
 
 
 
Tubulin-bindi..(2)
 
 
 
Bcl-2 like(2)
 
 
DUF3371(2)
 
 
DUF3652(2)
 
 
BioAssay Types:
Confirmatory(112)
 
 
 
 
Literature(99)
 
 
 
 
 
Screening(25)
 
 
BioActivity Types:
Potency(49)
 
 
 
 
IC50(6)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 175    Data Row: 249   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103301322]
IC50 0.31623Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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2
[SID103301322]
IC50 0.31623Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
3
[SID103301322]
IC50 0.31623Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
4
[SID103301322]
IC50 0.31623Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
5
[SID103301322]
IC50 0.31623Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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6
[SID103301322]
IC50 0.32Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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7
[SID103301322]
IC50 0.32Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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8
[SID103301322]
IC50 0.32Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
9
[SID103301322]
IC50 0.32Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
10
[SID103301322]
IC50 0.32Inhibition of human ERG channel [AID397743, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
11
[SID103301322]
IC50 0.32359Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
12
[SID103301322]
IC50 0.32359Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
13
[SID103301322]
IC50 0.32359Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
14
[SID103301322]
IC50 0.32359Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
15
[SID103301322]
IC50 0.32359Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique [AID408340, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
16
[SID103301322]
IC50 0.32359Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
17
[SID103301322]
IC50 0.32359Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
18
[SID103301322]
IC50 0.32359Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
19
[SID103301322]
IC50 0.32359Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
20
[SID103301322]
IC50 0.32359Inhibition of human Potassium channel HERG expressed in mammalian cells [AID161281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
21
[SID103301322]
IC50 0.54954Inhibitory concentration against potassium channel HERG [AID243151, Type: Literature]
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22
[SID26756521]
Potency 1.5101Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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23
[SID26756521]
Potency 5.6234qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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24
[SID26756521]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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25
[SID85209561]
 Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
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26
[SID447728]
 NCI AIDS Antiviral Assay [AID179, Type: confirmatory]
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27
[SID48416224]
 DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
View
28
[SID26756521]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
View
29
[SID26756521]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_45, Type: Literature]
View
30
[SID26756521]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_53, Type: Literature]
View
31
[SID26756521]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_55, Type: Literature]
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32
[SID26756521]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_57, Type: Literature]
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33
[SID103301322]
 logD (measured by HPLC) (as log k') [AID23959, Type: Literature]
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34
[SID103301322]
 logD (measured by HPLC) (as log k') [AID23965, Type: Literature]
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35
[SID103301322]
 logD (measured by HPLC) (as log k') [AID23968, Type: Literature]
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36
[SID103301322]
 logD (measured by HPLC) (as log k') [AID23970, Type: Literature]
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37
[SID103301322]
 logD (measured by HPLC) (as log k') [AID23971, Type: Literature]
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38
[SID103301322]
 Partition coefficient (logD, measured by HPLC, log k') [AID23973, Type: Literature]
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39
[SID103301322]
 Partition coefficient (logD) (HPLC) [AID26294, Type: Literature]
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40
[SID103301322]
 Partition coefficient (logD) (HPLC) [AID26295, Type: Literature]
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41
[SID103301322]
 Partition coefficient (logD7.4) [AID26296, Type: Literature]
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42
[SID103301322]
 Lipophilicity, log D at pH 7.4 by liquid chromatography [AID395324, Type: Literature]
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43
[SID103301322]
 Lipophilicity, log P by microemulsion electrokinetic chromatography [AID395325, Type: Literature]
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44
[SID103301322]
 Fraction unbound in rat brain [AID395326, Type: Literature]
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45
[SID103301322]
 Dissociation constant, pKa by capillary electrophoresis [AID395327, Type: Literature]
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46
[SID26756521]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
47
[SID103301322]
 Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset [AID588208, Type: Literature]
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48
[SID103301322]
 Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset [AID588220, Type: Literature]
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49
[SID103301322]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
View
50
[SID103301322]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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