Meclofenoxate (CID 4039) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(3)
 
 
Inactive(291)
 
 
Inconclusive(35)
 
 
Unspecified(11)
 
 
Top Targets:
p450(20)
 
 
 
 
 
PLN02808(5)
 
 
P53(5)
 
 
Firefly Luc l..(4)
 
 
HIF-1a CTAD(4)
 
 
 
BioAssay Types:
Confirmatory(220)
 
 
 
 
Literature(73)
 
 
 
 
Screening(19)
 
 
BioActivity Types:
Potency(175)
 
 
 
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 203    Data Row: 340   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID11111000]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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2
[SID11111000]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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3
[SID11111000]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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4
[SID11110999]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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5
[SID11110999]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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6
[SID11110999]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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7
[SID11111000]
 Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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8
[SID11111000]
 Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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9
[SID103252134]
IC50 500Inhibitory activity against Plasmodium falciparum [AID158688, Type: Literature]
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10
[SID11111000]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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11
[SID103252134]
 Time of recovery of righting reflux (RRT) in seconds was measured after administration of 200 mg/kg perorally in mice for the promotional effect on recovery from coma [AID119185, Type: Literature]
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12
[SID103252134]
 Time of recovery of spontaneous movement (SMT) in seconds was measured after administration of 200 mg/kg perorally in mice for the promotional effect on recovery from coma [AID119402, Type: Literature]
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13
[SID103252134]
 Antihypoxic effect tested by the survival time (SVT) in mice at a dose of 100 mg/kg [AID119554, Type: Literature]
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14
[SID103252134]
 Antihypoxic effect by the survival time (SVT) in mice at a dose of 3 mg/kg administered intravenously in mice [AID119565, Type: Literature]
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15
[SID103252134]
 Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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16
[SID103252134]
 Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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17
[SID103252134]
 Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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18
[SID11111000]
 Cytochrome panel assay with activity outcomes [AID1851, Type: other]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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19
[SID11111000]
 Cytochrome panel assay with activity outcomes [AID1851, Type: other]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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20
[SID11110999]
 Cytochrome panel assay with activity outcomes [AID1851, Type: other]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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21
[SID11110999]
 Cytochrome panel assay with activity outcomes [AID1851, Type: other]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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22
[SID11111000]
Potency 0.2818qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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23
[SID11111000]
Potency 0.2818qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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24
[SID11111000]
Potency 0.5725Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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25
[SID11111000]
Potency 0.9762S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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26
[SID11110999]
Potency 1.2589qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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27
[SID11110999]
Potency 1.2589qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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28
[SID11110999]
Potency 1.2589qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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29
[SID11111000]
Potency 2.5575Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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30
[SID11111000]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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31
[SID11111000]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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32
[SID90341454]
Potency 25.1189qHTS for Inhibitors of Glutaminase (GLS): LOPAC Validation [AID624146, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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33
[SID90341454]
Potency 42.5615qHTS Validation Assay to Find Inhibitors of Pin1 [AID504536, Type: confirmatory]PIN1 gene product [Homo sapiens] [gi:5453898]
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34
[SID90341454]
Potency 42.5615qHTS Validation Assay to Find Inhibitors of Pin1 [AID504536, Type: confirmatory]PIN1 gene product [Homo sapiens] [gi:5453898]
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35
[SID11110999]
Potency qHTS Assay for Activators of Human Muscle Pyruvate Kinase [AID954, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286420]
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36
[SID11110999]
Potency qHTS Assay for Activators of Human Muscle Pyruvate Kinase [AID954, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286420]
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37
[SID11110999]
Potency qHTS Assay for Activators of Human Muscle Pyruvate Kinase [AID954, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286420]
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38
[SID11110999]
Potency qHTS Assay for Inhibitors of Human Muscle Pyruvate Kinase [AID958, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286420]
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39
[SID11110999]
Potency qHTS Assay for Inhibitors of Human Muscle Pyruvate Kinase [AID958, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286420]
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40
[SID11110999]
Potency qHTS Assay for Inhibitors of Human Muscle Pyruvate Kinase [AID958, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286420]
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41
[SID11111000]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF [AID1454, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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42
[SID11111000]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF [AID1454, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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43
[SID11111000]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF [AID1454, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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44
[SID11111000]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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45
[SID11111000]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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46
[SID11111000]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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47
[SID11110999]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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48
[SID11110999]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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49
[SID11110999]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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50
[SID90341454]
Potency Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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