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4-aminophenol (CID 403) - Compound BioActivity Data
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BioActivity Outcomes:
Active(282)
 
 
Inactive(281)
 
 
Inconclusive(178)
 
 
Unspecified(31)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
 
 
NR LBD AR(23)
 
 
 
 
NR LBD ER(23)
 
 
 
NR LBD GR(14)
 
 
 
 
NR LBD TR(13)
 
 
 
 
BioAssay Types:
Confirmatory(381)
 
 
 
 
 
Screening(109)
 
 
 
Summary(63)
 
 
 
 
Literature(33)
 
 
 
 
BioActivity Types:
Potency(375)
 
 
 
 
 
Ki(15)
 
 
 
IC50(15)
 
 
 
 
 
EC50(4)
 
 
 
 
AC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 436    Data Row: 772   Total Pages: 39   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206793]
Potency-Replicate_1 0.8413qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144208228]
Potency-Replicate_1 0.897qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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3
[SID144206793]
Ratio Potency (uM) 1.10053qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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4
[SID144208228]
Ratio Potency (uM) 1.24292qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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5
[SID144207026]
Potency-Replicate_1 3.0638qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
6
[SID17388802]
Potency 3.1623qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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7
[SID17388802]
Potency 3.1623qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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8
[SID144207026]
Ratio Potency (uM) 4.00798qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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9
[SID17388802]
Potency 4.4668qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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10
[SID144206793]
Potency-Replicate_1 5.308qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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11
[SID144207026]
Ratio Potency (uM) 5.4941qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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12
[SID144206793]
Potency-Replicate_1 5.9557qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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13
[SID144206793]
Potency 6.3096qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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14
[SID144206793]
Potency 6.3096qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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15
[SID144206793]
Potency-Replicate_1 6.6824qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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16
[SID17388802]
Potency 6.6824qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
View
17
[SID17388802]
Potency 7.0795qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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18
[SID17388802]
Potency 7.4978qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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19
[SID144206793]
Potency-Replicate_1 7.4978qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
20
[SID144207026]
Potency 7.6959qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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