Bookmark and Share
phenylmethylpyrazolone (CID 4021) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(52)
 
 
Inactive(1558)
 
 
Inconclusive(106)
 
 
Unspecified(208)
 
 
Top Targets:
7tm 4(81)
 
 
 
NR LBD PPAR(40)
 
 
 
 
NR LBD ER(30)
 
 
 
 
NR LBD AR(26)
 
 
 
 
NR LBD TR(25)
 
 
BioAssay Types:
Confirmatory(922)
 
 
 
 
 
Screening(635)
 
 
 
 
Literature(169)
 
 
 
 
 
Summary(72)
 
 
 
 
BioActivity Types:
Potency(717)
 
 
 
 
 
IC50(177)
 
 
 
 
EC50(15)
 
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1334    Data Row: 1924   Total Pages: 97   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103219212]
IC50 0.25Hydroxy radical scavenging activity by ESR spin-trapping method [AID298289, Type: Literature]
View
2
[SID855774]
AC50_uM 2.753Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
3
[SID855774]
EC50_uM 2.95Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
4
[SID855774]
EC50_uM 3.099Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation [AID434968, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
5
[SID855774]
AC50_uM 3.243Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity [AID449750, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
6
[SID26757432]
Potency 3.9811Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View
7
[SID26746991]
Potency 5.0119qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View
8
[SID17389763]
Potency 10qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View
9
[SID855774]
Potency 10qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View
10
[SID144213136]
Potency-Replicate_1 10.8707qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
11
[SID144205630]
Potency-Replicate_1 11.8832qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
12
[SID144208945]
AhR Potency (uM) 16.0534qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
13
[SID144205630]
Ratio Potency (uM) 16.3953qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
14
[SID103219212]
IC50 17Antioxidant activity against Fe2SO4/ascorbate-induced lipid peroxidation in Wistar rat liver microsomal membrane by TBARS assay [AID412356, Type: Literature]
View
15
[SID144213136]
AhR Potency (uM) 20.0875qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
16
[SID17389763]
Potency 25.1189qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
17
[SID144205630]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
18
[SID103219212]
IC50 27Antioxidant effect assessed as DPPH radical scavenging activity [AID283751, Type: Literature]
View
19
[SID103219212]
IC50 29.3Scavenging activity against DPPH [AID226891, Type: Literature]
View
20
[SID144208945]
Potency-Replicate_1 30.8249qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View