Hydrogen Sulfide (CID 402) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(4)
 
 
Unspecified(3)
 
 
Top Targets:
alpha CA I II..(2)
 
 
alpha CA VI(1)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
Ki(5)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103770722]
Ki 0.6Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assay [AID552127, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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2
[SID103770722]
Ki 40Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assay [AID552128, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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3
[SID103770722]
Ki 580Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay [AID552130, Type: Literature]
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4
[SID103770722]
Ki 710Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assay [AID552129, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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5
[SID103770722]
Ki 3940Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay [AID552131, Type: Literature]
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6
[SID474028]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID330, Type: other]
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7
[SID474028]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID328, Type: other]
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8
[SID474028]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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9
[SID474028]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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