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Vecuronium Bromide (CID 39765) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(52)
 
 
Inconclusive(41)
 
 
Unspecified(24)
 
 
Top Targets:
Neur chan LBD(4)
 
 
ABC MTABC3 MD..(3)
 
 
Bromo ALL-1(3)
 
 
Menin(2)
 
 
Geminin(2)
 
 
BioAssay Types:
Literature(77)
 
 
 
 
 
Confirmatory(29)
 
 
 
BioActivity Types:
Potency(28)
 
 
 
IC50(5)
 
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 53    Data Row: 119   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123097011]
IC50 4.5Inhibition of apamin-sensitive SKCa channel of guinea-pig hepatocytes [AID241212, Type: Literature]
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2
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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3
[SID123097011]
IC50 0.082GRAC: human AChR-alpha1 commonly used antagonist [AID540514, Type: other]Acetylcholine receptor subunit alpha [gi:113071]
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4
[SID123097011]
IC50 0.082GRAC: human AChR-alpha1 commonly used antagonist [AID540514, Type: other]Acetylcholine receptor subunit gamma [gi:126302510]
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5
[SID123097011]
IC50 0.082GRAC: human AChR-alpha1 commonly used antagonist [AID540514, Type: other]Acetylcholine receptor subunit delta [gi:543759]
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6
[SID123097011]
IC50 0.082GRAC: human AChR-alpha1 commonly used antagonist [AID540514, Type: other]Acetylcholine receptor subunit beta [gi:21903373]
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7
[SID123097011]
Ki 120TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes [AID679498, Type: other]Solute carrier family 22 member 1 [gi:313104181]
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8
[SID123097011]
Ki 232TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing HeLa cells [AID681146, Type: other]Solute carrier family 22 member 1 [gi:313104181]
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9
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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10
[SID123097011]
TP_TRANSPORTER: transepithelial transport (basal to apical) in Mdr1b-expressing LLC-PK1 cells [AID679471, Type: other]Multidrug resistance protein 1B [gi:126927]
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11
[SID123097011]
TP_TRANSPORTER: transepithelial transport (basal to apical) in MDR1-expressing LLC-PK1 cells [AID679456, Type: other]Multidrug resistance protein 1 [gi:238054374]
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12
[SID123097011]
TP_TRANSPORTER: transepithelial transport (basal to apical) in Mdr1a-expressing LLC-PK1 cells [AID679122, Type: other]Multidrug resistance protein 1A [gi:239938877]
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13
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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14
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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15
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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16
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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17
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests [AID625283, Type: Literature]
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18
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty [AID625290, Type: Literature]
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19
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal [AID625291, Type: Literature]
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20
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score [AID625292, Type: Literature]
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21
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure [AID625284, Type: Literature]
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22
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis [AID625285, Type: Literature]
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23
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis [AID625286, Type: Literature]
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24
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly [AID625287, Type: Literature]
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25
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice [AID625288, Type: Literature]
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26
[SID123097011]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease [AID625289, Type: Literature]
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27
[SID92309078]
A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
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28
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_59, Type: Literature]
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29
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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30
[SID50112721]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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31
[SID50112721]
Potency S16 Schwann cell viability assay (CellTiter-Glo assay) [AID624031, Type: confirmatory]
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32
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_61, Type: Literature]
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33
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_49, Type: Literature]
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34
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_42, Type: Literature]
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35
[SID92309078]
A screen for compounds that inhibit nucleocapsid/RNA interactions in Rift Valley Fever Virus [AID651828, Type: other]Nucleoprotein [gi:127925]
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36
[SID50112721]
Potency Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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37
[SID50112721]
Potency qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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38
[SID50112721]
Potency VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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39
[SID50112721]
Potency qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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40
[SID50112721]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_1, Type: Literature]
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41
[SID50112721]
Potency qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS [AID602332, Type: confirmatory]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
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42
[SID50112721]
Potency qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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43
[SID50112721]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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44
[SID50112721]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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45
[SID50112721]
Potency qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction [AID2662, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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46
[SID50112721]
Potency qHTS of Trypanosoma Brucei Inhibitors [AID624173, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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47
[SID50112721]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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48
[SID50112721]
Potency qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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49
[SID50112721]
Potency qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase: hit validation [AID492961, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei] [gi:72386991]
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50
[SID50112721]
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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