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Lobeline (CID 3945) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(723)
 
 
Inconclusive(4)
 
 
Unspecified(13)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(19)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
G-alpha(7)
 
 
 
BioAssay Types:
Screening(509)
 
 
 
 
 
Confirmatory(198)
 
 
 
 
 
Literature(22)
 
 
 
 
BioActivity Types:
Potency(142)
 
 
 
 
 
IC50(42)
 
 
EC50(8)
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 681    Data Row: 746   Total Pages: 38   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103177971]
Ki 0.12Inhibitory constant for cytochrome P450 2D6 [AID150609, Type: Literature]Cytochrome P450 2D6 [gi:84028191]
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2
[SID103177971]
Ki 6.26Displacement of [3H]MLA from alpha7 nAChR in rat brain homogenate by liquid scintillation spectrophotometry [AID459740, Type: Literature]
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3
[SID16953570]
Potency 18.3564qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells [AID2685, Type: confirmatory]
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4
[SID16953570]
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment [AID2417, Type: screening]polypyrimidine tract-binding protein 1 isoform a [Homo sapiens] [gi:4506243]
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5
[SID16953570]
Leishmania major promastigote HTS [AID1063, Type: screening]
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6
[SID16953570]
qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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7
[SID16953570]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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8
[SID103177971]
Selectivity ratio of Ki for rat VMAT2 to Ki for rat alpha4beta2 nAChR [AID459751, Type: Literature]
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9
[SID103177971]
Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset [AID588220, Type: Literature]
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10
[SID103177971]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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11
[SID103177971]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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12
[SID16953570]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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13
[SID103177971]
Maximum percent of enhancement of binding. [AID30377, Type: Literature]
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14
[SID103177971]
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a particular dose range 5E-9 - 1.5E-8 was reported [AID30529, Type: Literature]
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15
[SID103177971]
Selectivity for VMAT2 over DAT [AID271311, Type: Literature]
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16
[SID103177971]
Selectivity for VMAT2 over SERT [AID271312, Type: Literature]
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17
[SID16953570]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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18
[SID16953570]
Potency qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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19
[SID103177971]
Ratio of Ki for displacement of [3H]DTBZ from VMAT2 dihydrotetrabenazine binding site in rat brain synaptic vesicle to Ki for inhibition of [3H]dopamine uptake at VMAT2 in rat brain synaptic vesicle [AID440784, Type: Literature]Synaptic vesicular amine transporter [gi:34978379]
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20
[SID16953570]
Potency 2.5119qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase 1 [gi:44888968]
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