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Ritonavir (CID 392622) - Compound BioActivity Data
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BioActivity Outcomes:
Active(251)
 
 
Inactive(495)
 
 
Inconclusive(64)
 
 
Unspecified(668)
 
 
Top Targets:
p450(33)
 
 
 
 
 
7TM GPCR Srx(28)
 
 
 
 
7TM GPCR Srsx(25)
 
 
 
 
ABC MTABC3 MD..(23)
 
 
 
NR LBD PPAR(16)
 
 
 
 
BioAssay Types:
Literature(584)
 
 
 
 
 
Confirmatory(415)
 
 
 
 
 
Screening(235)
 
 
 
 
Summary(39)
 
 
 
 
BioActivity Types:
Potency(256)
 
 
 
 
IC50(214)
 
 
 
 
EC50(143)
 
 
 
 
 
Ki(36)
 
 
 
Kd(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1329    Data Row: 1478   Total Pages: 74   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103244854]
Ki 1.5e-05Inhibition constant of ritonavir towards HIV protease was determined [AID82914, Type: confirmatory]
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2
[SID103244854]
Ki 1.5e-05Tested for inhibitor binding of wild-type HIV PR [AID82946, Type: Literature]
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3
[SID46392172]
Ki 1.5e-05Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Hiv-1 Protease Dimer Complexed With A-84538 [gi:413915763]
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4
[SID46392172]
Ki 1.5e-05Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Hiv-1 Protease Dimer Complexed With A-84538 [gi:413915763]
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5
[SID46392172]
Ki 1.5e-05Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Hiv-1 Protease Dimer Complexed With A-84538 [gi:413915764]
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6
[SID46392172]
Ki 1.5e-05Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Hiv-1 Protease Dimer Complexed With A-84538 [gi:413915764]
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7
[SID103244854]
Ki 2e-05Inhibitory activity against purified HIV protease [AID82795, Type: confirmatory]
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8
[SID103244854]
Ki 2e-05Inhibition of HIV protease [AID160300, Type: Literature]Pol polyprotein [gi:75593047]
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9
[SID103244854]
Ki 3.4e-05Inhibition of HIV1 protease [AID374591, Type: Literature]
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10
[SID103244854]
EC50 5.5e-05The activity against mutant HIV molecular clone wt (pNL4-3) was determined [AID82723, Type: confirmatory]
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11
[SID103244854]
Ki 6.2e-05Dissociation constant obtained by inhibition of Wild-type protease [AID219260, Type: Literature]
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12
[SID103244854]
Ki 9.8e-05Inhibition of HIV1 protease [AID321660, Type: Literature]
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13
[SID103244854]
Ki 0.00012Tested for inhibitor binding of D25N/V82A mutant of HIV PR [AID82944, Type: Literature]
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14
[SID103244854]
EC50 0.00023The activity against mutant HIV molecular clone V82A was determined [AID82600, Type: confirmatory]
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15
[SID103244854]
EC50 0.000308The activity against mutant HIV molecular clone V82F was determined [AID82601, Type: confirmatory]
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16
[SID103244854]
EC50 0.000316The activity against mutant HIV molecular clone V82T was determined [AID82602, Type: confirmatory]
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17
[SID103244854]
Ki 0.00037Binding affinity to inhibit the purified wild-type HIV-1 Protease [AID160316, Type: Literature]Pol polyprotein [gi:75593047]
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18
[SID103244854]
Ki 0.00037Binding affinity for HIV -1 Protease [AID82295, Type: Literature]Pol polyprotein [gi:75593047]
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19
[SID103244854]
Ki 0.00037Affinity against HIV protease [AID162710, Type: Literature]Pol polyprotein [gi:75593047]
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20
[SID103244854]
Ki 0.00037Inhibitory activity against HIV-1 protease [AID163487, Type: Literature]Pol polyprotein [gi:75593047]
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