Bookmark and Share
lauric acid (CID 3893) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(845)
 
 
Inconclusive(79)
 
 
Unspecified(37)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
7TM GPCR Srx(19)
 
 
NR LBD AR(18)
 
 
 
 
NR LBD ER(18)
 
 
 
7TM GPCR Srsx(15)
 
 
BioAssay Types:
Confirmatory(535)
 
 
 
 
 
Screening(302)
 
 
 
Literature(52)
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(485)
 
 
 
 
 
IC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 675    Data Row: 968   Total Pages: 20   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209347]
Ratio Potency (uM) 10.9917qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
2
[SID144209347]
Potency-Replicate_1 27.3616qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
3
[SID144209347]
Potency-Replicate_1 61.2549qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
4
[SID144209347]
Potency-Replicate_1 61.2549qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
5
[SID144209347]
Potency-Replicate_1 61.2549qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
6
[SID56462800]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2) [AID492953, Type: screening]platelet-activating factor acetylhydrolase IB subunit beta isoform b [Homo sapiens] [gi:296080766]
View
7
[SID56462800]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
View
8
[SID103329807]
LD50 10Cytotoxicity against mouse RAW264.7 cells [AID627981, Type: Literature]
View
9
[SID103329807]
MIC 62.5Antitubercular activity against Mycobacterium tuberculosis 90-221387 [AID403754, Type: Literature]
View
10
[SID103329807]
IC50 1980Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
View
11
[SID103329807]
IC50 1995.26Inhibition of Bacillus subtilis spore germination, activity is expressed as log of the reciprocal of Casida's I50 value. [AID40935, Type: Literature]
View
12
[SID103329807]
Inhibition of Bacillus subtilis PCI219 spore germination, expressed as log 1/I50 [AID40936, Type: Literature]
View
13
[SID103329807]
Sterilization time for contact germicidal efficiency (CGE) of salt was tested against Pseudomonas aeruginosa at pH 7.0, concentration 610 ppm [AID164418, Type: Literature]
View
14
[SID103329807]
Sterilization time for contact germicidal efficiency (CGE) of salt was tested against Staphylococcus aureus at pH 7.0, concentration 610 ppm [AID207085, Type: Literature]
View
15
[SID103329807]
Sterilization time for contact germicidal efficiency (CGE) of salt was tested against Streptococcus pyogenes at pH 7.0, concentration 610 ppm [AID210082, Type: Literature]
View
16
[SID103329807]
Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID332912, Type: Literature]
View
17
[SID103329807]
Antimicrobial activity against Bacillus subtilis ATCC 9372 after 2 days by twofold serial broth dilution method [AID334989, Type: Literature]
View
18
[SID103329807]
Antimicrobial activity against Brevibacterium ammoniagenes ATCC 6872 after 2 days by twofold serial broth dilution method [AID334990, Type: Literature]
View
19
[SID103329807]
Antimicrobial activity against Propionibacterium acnes ATCC 11827 after 2 days by twofold serial broth dilution method [AID334991, Type: Literature]
View
20
[SID103329807]
Antimicrobial activity against Staphylococcus aureus ATCC 12598 after 2 days by twofold serial broth dilution method [AID334992, Type: Literature]
View
21
[SID103329807]
Antimicrobial activity against Streptococcus mutans ATCC 25175 after 2 days by twofold serial broth dilution method [AID334993, Type: Literature]
View
22
[SID103329807]
Antimicrobial activity against Escherichia coli ATCC 9637 after 2 days by twofold serial broth dilution method [AID334994, Type: Literature]
View
23
[SID103329807]
Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 after 2 days by twofold serial broth dilution method [AID334995, Type: Literature]
View
24
[SID103329807]
Antimicrobial activity against Enterobacter aerogenes ATCC 13048 after 2 days by twofold serial broth dilution method [AID334996, Type: Literature]
View
25
[SID103329807]
Antimicrobial activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by twofold serial broth dilution method [AID334997, Type: Literature]
View
26
[SID103329807]
Antimicrobial activity against Candida utilis ATCC 9226 after 2 days by twofold serial broth dilution method [AID334998, Type: Literature]
View
27
[SID103329807]
Antimicrobial activity against Pityrosporum ovale ATCC 14521 by twofold serial broth dilution method [AID334999, Type: Literature]
View
28
[SID103329807]
Antimicrobial activity against Penicillium chrysogenum ATCC 10106 after 5 days by twofold serial broth dilution method [AID335000, Type: Literature]
View
29
[SID103329807]
Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 after 24 hrs by macrobroth dilution method [AID390912, Type: Literature]
View
30
[SID103329807]
Antibacterial activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by macrobroth dilution method [AID390920, Type: Literature]
View
31
[SID103329807]
Cytotoxicity against mouse RAW264.7 cells at 5 uM [AID627980, Type: Literature]
View
32
[SID103329807]
Antibacterial activity against Staphylococcus aureus by broth microdilution method [AID597407, Type: Literature]
View
33
[SID103329807]
Antibacterial activity against methicillin-resistant Staphylococcus aureus by broth microdilution method [AID597408, Type: Literature]
View
34
[SID103329807]
Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay [AID492140, Type: Literature]
View
35
[SID17388953]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
36
[SID17389665]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
37
[SID103329807]
Dissociation constant (pKa) [AID25611, Type: Literature]
View
38
[SID103329807]
Partition coefficient (logD7.2) [AID26261, Type: Literature]
View
39
[SID103329807]
Partition coefficient (logP) [AID26793, Type: Literature]
View
40
[SID103329807]
Clinically relevant substrates of human liver microsomal P450 enzymes, isoform CYP2E1 [AID589037, Type: other]Cytochrome P450 2E1 [gi:117250]
View
41
[SID103329807]
Specific activity of expressed human recombinant UGT1A3 [AID624607, Type: Literature]UDP-glucuronosyltransferase 1-4 [gi:136731]
View
42
[SID56462800]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
43
[SID103329807]
Specific activity of expressed human recombinant UGT1A10 [AID624613, Type: Literature]UDP-glucuronosyltransferase 1-10 [gi:29839636]
View
44
[SID103329807]
Specific activity of expressed human recombinant UGT1A8 [AID624611, Type: Literature]UDP-glucuronosyltransferase 1-8 [gi:29839637]
View
45
[SID144213327]
Potency-Replicate_1 5.4483qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
46
[SID17389665]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View
47
[SID144209347]
Potency-Replicate_1 21.7341qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
48
[SID144213327]
Potency-Replicate_1 24.3365qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
View
49
[SID144213327]
Potency-Replicate_1 27.5391qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
50
[SID17389665]
Potency 29.8493qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View