lauric acid (CID 3893) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(648)
 
 
Inconclusive(29)
 
 
Unspecified(37)
 
 
Top Targets:
7TM GPCR Srx(15)
 
 
NR LBD PPAR(10)
 
 
 
NR LBD TR(8)
 
 
 
P53(7)
 
 
NR LBD ROR li..(6)
 
 
 
BioAssay Types:
Confirmatory(374)
 
 
 
 
Screening(260)
 
 
 
Literature(38)
 
 
 
BioActivity Types:
Potency(290)
 
 
 
 
IC50(13)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 556    Data Row: 716   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56462800]
 Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening]
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2
[SID56462800]
 Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2) [AID492953, Type: screening]platelet-activating factor acetylhydrolase IB subunit beta isoform b [Homo sapiens] [gi:296080766]
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3
[SID103329807]
LD50 10Cytotoxicity against mouse RAW264.7 cells [AID627981, Type: Literature]
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4
[SID103329807]
MIC 62.5Antitubercular activity against Mycobacterium tuberculosis 90-221387 [AID403754, Type: Literature]
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5
[SID103329807]
IC50 1980Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
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6
[SID103329807]
IC50 1995.26Inhibition of Bacillus subtilis spore germination, activity is expressed as log of the reciprocal of Casida's I50 value. [AID40935, Type: Literature]
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7
[SID103329807]
IC50 1995.26Inhibition of Bacillus subtilis PCI219 spore germination, expressed as log 1/I50 [AID40936, Type: Literature]
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8
[SID103329807]
 Sterilization time for contact germicidal efficiency (CGE) of salt was tested against Pseudomonas aeruginosa at pH 7.0, concentration 610 ppm [AID164418, Type: Literature]
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9
[SID103329807]
 Sterilization time for contact germicidal efficiency (CGE) of salt was tested against Staphylococcus aureus at pH 7.0, concentration 610 ppm [AID207085, Type: Literature]
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10
[SID103329807]
 Sterilization time for contact germicidal efficiency (CGE) of salt was tested against Streptococcus pyogenes at pH 7.0, concentration 610 ppm [AID210082, Type: Literature]
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11
[SID103329807]
 Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID332912, Type: other]
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12
[SID103329807]
 Antimicrobial activity against Bacillus subtilis ATCC 9372 after 2 days by twofold serial broth dilution method [AID334989, Type: other]
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13
[SID103329807]
 Antimicrobial activity against Brevibacterium ammoniagenes ATCC 6872 after 2 days by twofold serial broth dilution method [AID334990, Type: other]
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14
[SID103329807]
 Antimicrobial activity against Propionibacterium acnes ATCC 11827 after 2 days by twofold serial broth dilution method [AID334991, Type: other]
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15
[SID103329807]
 Antimicrobial activity against Staphylococcus aureus ATCC 12598 after 2 days by twofold serial broth dilution method [AID334992, Type: other]
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16
[SID103329807]
 Antimicrobial activity against Streptococcus mutans ATCC 25175 after 2 days by twofold serial broth dilution method [AID334993, Type: other]
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17
[SID103329807]
 Antimicrobial activity against Escherichia coli ATCC 9637 after 2 days by twofold serial broth dilution method [AID334994, Type: other]
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18
[SID103329807]
 Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 after 2 days by twofold serial broth dilution method [AID334995, Type: other]
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19
[SID103329807]
 Antimicrobial activity against Enterobacter aerogenes ATCC 13048 after 2 days by twofold serial broth dilution method [AID334996, Type: other]
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20
[SID103329807]
 Antimicrobial activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by twofold serial broth dilution method [AID334997, Type: other]
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21
[SID103329807]
 Antimicrobial activity against Candida utilis ATCC 9226 after 2 days by twofold serial broth dilution method [AID334998, Type: other]
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22
[SID103329807]
 Antimicrobial activity against Pityrosporum ovale ATCC 14521 by twofold serial broth dilution method [AID334999, Type: other]
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23
[SID103329807]
 Antimicrobial activity against Penicillium chrysogenum ATCC 10106 after 5 days by twofold serial broth dilution method [AID335000, Type: other]
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24
[SID103329807]
 Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 after 24 hrs by macrobroth dilution method [AID390912, Type: Literature]
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25
[SID103329807]
 Antibacterial activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by macrobroth dilution method [AID390920, Type: Literature]
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26
[SID103329807]
 Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay [AID492140, Type: Literature]
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27
[SID103329807]
 Antibacterial activity against Staphylococcus aureus by broth microdilution method [AID597407, Type: Literature]
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28
[SID103329807]
 Antibacterial activity against methicillin-resistant Staphylococcus aureus by broth microdilution method [AID597408, Type: Literature]
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29
[SID17388953]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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30
[SID17389665]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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31
[SID103329807]
 Clinically relevant substrates of human liver microsomal P450 enzymes, isoform CYP2E1 [AID589037, Type: other]Cytochrome P450 2E1 [gi:117250]
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32
[SID103329807]
 Dissociation constant (pKa) [AID25611, Type: Literature]
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33
[SID103329807]
 Partition coefficient (logD7.2) [AID26261, Type: Literature]
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34
[SID103329807]
 Partition coefficient (logP) [AID26793, Type: Literature]
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35
[SID103329807]
 Cytotoxicity against mouse RAW264.7 cells at 5 uM [AID627980, Type: Literature]
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36
[SID56462800]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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37
[SID56462800]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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38
[SID103329807]
 Specific activity of expressed human recombinant UGT1A10 [AID624613, Type: Literature]UDP-glucuronosyltransferase 1-10 [gi:29839636]
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39
[SID103329807]
 Specific activity of expressed human recombinant UGT1A8 [AID624611, Type: Literature]UDP-glucuronosyltransferase 1-8 [gi:29839637]
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40
[SID103329807]
 Specific activity of expressed human recombinant UGT1A3 [AID624607, Type: Literature]UDP-glucuronosyltransferase 1-4 [gi:136731]
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41
[SID17389665]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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42
[SID17389665]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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43
[SID17389665]
Potency 29.8493qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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44
[SID17389665]
Potency 29.8493qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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45
[SID17389665]
Potency 29.8493qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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46
[SID17389665]
Potency 29.8493qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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47
[SID17389665]
Potency 29.8493qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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48
[SID56462800]
Potency 31.6228qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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49
[SID17388953]
Potency 66.8242qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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50
[SID17388953]
Potency 66.8242qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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