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Mimosine (CID 3862) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(171)
 
 
Inconclusive(26)
 
 
Unspecified(13)
 
 
Top Targets:
PLDc mTdp1 2(3)
 
 
GH27(2)
 
 
G glu transpe..(2)
 
 
RNA dep RNAP(2)
 
 
HSD10-like SD..(2)
 
 
BioAssay Types:
Confirmatory(127)
 
 
 
Literature(9)
 
 
 
 
Screening(7)
 
 
BioActivity Types:
Potency(65)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 193    Data Row: 212   Total Pages: 11   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103557939]
IC50 32Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum [AID312521, Type: Literature]
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2
[SID103557939]
IC50 39Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum [AID312522, Type: Literature]
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3
[SID103557939]
ED50 100Antitrypanosomal activity against Trypanosoma brucei brucei TC221 [AID312529, Type: Literature]
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4
[SID8149677]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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5
[SID8149677]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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6
[SID8149677]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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7
[SID8149677]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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8
[SID8149677]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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9
[SID8149677]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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10
[SID8149677]
Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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11
[SID8149677]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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12
[SID8149677]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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13
[SID8149677]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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14
[SID103557939]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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15
[SID103557939]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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16
[SID11537750]
NMR Based Screening Assay for the substrate binding domain of the chaperone DnaK [AID1033, Type: screening]DnaK protein homolog [Escherichia coli] [gi:216546]
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17
[SID26748432]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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18
[SID26748432]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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19
[SID99302088]
A screen for compounds that inhibit processive DNA synthesis of vaccinia virus [AID493162, Type: other]DNA polymerase [Vaccinia virus] [gi:335756]
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20
[SID26748432]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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