benzylsuccinic acid (CID 3858) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(76)
 
 
Unspecified(6)
 
 
Top Targets:
DSPc(2)
 
 
23DHB-AMP lg(1)
 
 
CAP ED(1)
 
 
Chorismate bi..(1)
 
 
DUF3346(1)
 
 
BioAssay Types:
Confirmatory(60)
 
 
 
Literature(12)
 
 
 
 
Screening(5)
 
 
BioActivity Types:
IC50(8)
 
 
 
 
Ki(4)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 88    Data Row: 88   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103395216]
IC50 0.4In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasma [AID48477, Type: Literature]
View
2
[SID103395216]
Ki 0.45The compound was evaluated for the inhibition of Carboxypeptidase A [AID48493, Type: Literature]
View
3
[SID103395216]
Ki 0.5Inhibition of bovine carboxypeptidase A1 [AID429443, Type: Literature]Carboxypeptidase A1 [gi:115878]
View
4
[SID103395216]
IC50 1.6In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasma [AID48496, Type: Literature]Carboxypeptidase B2 [gi:317373332]
View
5
[SID103395216]
Ki 10Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system [AID429518, Type: Literature]Carboxypeptidase B [gi:20532382]
View
6
[SID103395216]
Ki 11.9Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system [AID429442, Type: Literature]Carboxypeptidase B precursor [gi:122124524]
View
7
[SID103395216]
IC50 50In vitro inhibition of purified Carboxypeptidase N (CPN) by clot lysis assay in human plasma [AID48648, Type: Literature]
View
8
[SID103395216]
IC50 50In vitro inhibition of thrombin-activatable fibrinolysis was determined by clot lysis assay using human plasma [AID89377, Type: Literature]
View
9
[SID103395216]
IC50 50In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasma [AID48647, Type: Literature]Carboxypeptidase M [gi:14916957]
View
10
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-231/ATCC Breast cell line [AID95, Type: confirmatory]
View
11
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line [AID13, Type: confirmatory]
View
12
[SID103395216]
 Concentration of compound that gives 50% of the maximum acceleration of lysis was determined by clot lysis assay using human plasma [AID89210, Type: Literature]
View
13
[SID92221715]
 A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities [AID588519, Type: Literature]Chain A, Poliovirus Polymerase With Gtp [gi:52695378]
View
14
[SID92221715]
 A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme MbtI [AID493033, Type: other]Isochorismate synthase/isochorismate-pyruvate lyase mbtI [gi:81706979]
View
15
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H460 Non-Small Cell Lung cell line [AID7, Type: confirmatory]
View
16
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the HOP-62 Non-Small Cell Lung cell line [AID9, Type: confirmatory]
View
17
[SID17439402]
IC50 High Throughput Screening Assay for Hsp70 Inhibitors [AID583, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
View
18
[SID8065374]
 HIV-1 RNase H Inhibition [AID372, Type: screening]Chain A, Solution Structure Of The Rnase H Domain Of The Hiv-1 Reverse Transcriptase In The Presence [gi:28949057]
View
19
[SID92221715]
 A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis [AID540299, Type: Literature]naphthoate synthase [Mycobacterium tuberculosis H37Rv] [gi:15607688]
View
20
[SID92221715]
 A screen for compounds that inhibit replication of Vibrio cholerae chromosome II [AID504770, Type: other]hypothetical protein VC_A0002 [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657380]
View
21
[SID92221715]
 A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
View
22
[SID92221715]
 A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme BasE [AID485350, Type: screening]enterobactin synthase subunit E [Acinetobacter baumannii ATCC 17978] [gi:126642418]
View
23
[SID92221715]
 A screen for compounds that inhibit the activity of Staphylococcus aureus DNA helicase [AID485395, Type: other]replicative DNA helicase [Staphylococcus aureus subsp. aureus JH1] [gi:150392496]
View
24
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H522 Non-Small Cell Lung cell line [AID15, Type: confirmatory]
View
25
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the A549/ATCC Non-Small Cell Lung cell line [AID19, Type: confirmatory]
View
26
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the EKVX Non-Small Cell Lung cell line [AID21, Type: confirmatory]
View
27
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the LOX IMVI Melanoma cell line [AID23, Type: confirmatory]
View
28
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the M14 Melanoma cell line [AID25, Type: confirmatory]
View
29
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line [AID29, Type: confirmatory]
View
30
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the UACC-62 Melanoma cell line [AID31, Type: confirmatory]
View
31
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the UACC-257 Melanoma cell line [AID33, Type: confirmatory]
View
32
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-2 Melanoma cell line [AID35, Type: confirmatory]
View
33
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line [AID37, Type: confirmatory]
View
34
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-28 Melanoma cell line [AID39, Type: confirmatory]
View
35
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the PC-3 Prostate cell line [AID41, Type: confirmatory]
View
36
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line [AID43, Type: confirmatory]
View
37
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SF-268 Central Nervous System cell line [AID45, Type: confirmatory]
View
38
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SF-295 Central Nervous System cell line [AID47, Type: confirmatory]
View
39
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line [AID49, Type: confirmatory]
View
40
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SNB-19 Central Nervous System cell line [AID53, Type: confirmatory]
View
41
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the U251 Central Nervous System cell line [AID59, Type: confirmatory]
View
42
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the HT29 Colon cell line [AID65, Type: confirmatory]
View
43
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the COLO 205 Colon cell line [AID67, Type: confirmatory]
View
44
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the HCT-15 Colon cell line [AID71, Type: confirmatory]
View
45
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the KM12 Colon cell line [AID73, Type: confirmatory]
View
46
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Colon cell line [AID77, Type: confirmatory]
View
47
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Colon cell line [AID79, Type: confirmatory]
View
48
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the SW-620 Colon cell line [AID81, Type: confirmatory]
View
49
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the MCF7 Breast cell line [AID83, Type: confirmatory]
View
50
[SID83261]
 NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Breast cell line [AID85, Type: confirmatory]
View