octanoic acid (CID 379) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(680)
 
 
Inconclusive(17)
 
 
Unspecified(31)
 
 
Top Targets:
NR LBD PPAR(10)
 
 
 
7TM GPCR Srx(9)
 
 
NR LBD TR(8)
 
 
P53(7)
 
 
NR LBD ROR li..(6)
 
 
BioAssay Types:
Confirmatory(385)
 
 
 
 
Screening(219)
 
 
 
 
Literature(78)
 
 
 
 
BioActivity Types:
Potency(304)
 
 
 
 
IC50(10)
 
 
 
Ki(3)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 495    Data Row: 729   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85272331]
 Luminescence-based primary cell-based high throughput screening assay to identify inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1) [AID504766, Type: screening]NR0B1 gene product [Homo sapiens] [gi:5016090]
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2
[SID103329806]
Ki 5.41TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cells [AID678821, Type: other]
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3
[SID103329806]
Ki 8.6TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT3-expressing S2 cells [AID678814, Type: other]
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4
[SID103329806]
Ki 235.5TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT4-expressing S2 cells [AID678972, Type: other]
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5
[SID103329806]
IC50 53500Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
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6
[SID103329806]
IC50 53703.2Inhibition of Bacillus subtilis spore germination, activity is expressed as log of the reciprocal of Casida's I50 value. [AID40935, Type: Literature]
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7
[SID103329806]
IC50 53703.2Inhibition of Bacillus subtilis PCI219 spore germination, expressed as log 1/I50 [AID40936, Type: Literature]
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8
[SID103329806]
 Antibacterial activity against Bacillus subtilis ATCC 9372 after 2 days by broth dilution method [AID359935, Type: other]
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9
[SID103329806]
 Antibacterial activity against Brevibacterium ammoniagenes ATCC 6872 after 2 days by broth dilution method [AID359936, Type: other]
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10
[SID103329806]
 Antibacterial activity against Staphylococcus aureus ATCC 12598 after 2 days by broth dilution method [AID359937, Type: other]
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11
[SID103329806]
 Antibacterial activity against Streptococcus mutans ATCC 125175 after 2 days by broth dilution method [AID359938, Type: other]
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12
[SID103329806]
 Antibacterial activity against Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID359939, Type: other]
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13
[SID103329806]
 Antibacterial activity against Escherichia coli ATCC 9637 after 2 days by broth dilution method [AID359940, Type: other]
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14
[SID103329806]
 Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 2 days by broth dilution method [AID359941, Type: other]
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15
[SID103329806]
 Antibacterial activity against Enterobacter aerogenes ATCC 13048 after 2 days by broth dilution method [AID359942, Type: other]
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16
[SID103329806]
 Antifungal activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by broth dilution method [AID359943, Type: other]
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17
[SID103329806]
 Antifungal activity against Candida utilis ATCC 9226 after 2 days by broth dilution method [AID359944, Type: other]
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18
[SID103329806]
 Antibacterial activity against Proteus vulgaris ATCC 13315 after 2 days by broth dilution method [AID359945, Type: other]
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19
[SID103329806]
 Antifungal activity against Pityrosporum ovale ATCC 14521 after 3 days by broth dilution method [AID359946, Type: other]
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20
[SID103329806]
 Antifungal activity against Penicillium chrysogenum ATCC 10106 after 5 days by broth dilution method [AID359947, Type: other]
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21
[SID103329806]
 Antifungal activity against Trichophyton mentagrophytes ATCC 18748 after 5 days by broth dilution method [AID359948, Type: other]
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22
[SID103329806]
 Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay [AID492140, Type: Literature]
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23
[SID17388833]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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24
[SID17389655]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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25
[SID103329806]
 TP_TRANSPORTER: inhibition of Ochratoxin A uptake (OTA: 1 uM, Octanoate: 200 uM) in Xenopus laevis oocytes [AID681800, Type: other]
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26
[SID103329806]
 Dissociation constant (pKa) [AID25611, Type: Literature]
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27
[SID103329806]
 Partition coefficient (logD7.2) [AID26261, Type: Literature]
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28
[SID103329806]
 Partition coefficient (logP) [AID26793, Type: Literature]
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29
[SID17389655]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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30
[SID85272331]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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31
[SID85272331]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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32
[SID103329806]
 Specific activity of expressed human recombinant UGT1A10 [AID624613, Type: Literature]UDP-glucuronosyltransferase 1-10 [gi:29839636]
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33
[SID103329806]
 Specific activity of expressed human recombinant UGT1A8 [AID624611, Type: Literature]UDP-glucuronosyltransferase 1-8 [gi:29839637]
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34
[SID85272331]
Potency 0.2311A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
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35
[SID85272331]
 Luminescence-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) [AID602281, Type: screening]ABHD5 gene product [Homo sapiens] [gi:31542303]
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36
[SID124812774]
 A screen for small molecule inhibitors of the human deubiquitinating enzyme, UCH37 [AID588478, Type: other]ubiquitin C-terminal hydrolase UCH37 [Homo sapiens] [gi:4877999]
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37
[SID85272331]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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38
[SID85272331]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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39
[SID17389655]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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40
[SID17389655]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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41
[SID85272331]
 Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding. [AID504734, Type: screening]toll-like receptor 9 [Homo sapiens] [gi:194068499]
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42
[SID85272331]
 Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding. [AID504734, Type: screening]toll-like receptor 9 [Homo sapiens] [gi:194068499]
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43
[SID17389655]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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44
[SID17389655]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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45
[SID17389655]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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46
[SID17389655]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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47
[SID17389655]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_1, Type: Literature]
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48
[SID17389655]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_2, Type: Literature]
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49
[SID17389655]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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50
[SID17389655]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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