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Isoproterenol (CID 3779) - Compound BioActivity Data
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BioActivity Outcomes:
Active(112)
 
 
Inactive(250)
 
 
Inconclusive(50)
 
 
Unspecified(788)
 
 
Top Targets:
7TM GPCR Srsx(82)
 
 
 
 
7TM GPCR Srx(42)
 
 
 
 
p450(10)
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD PPAR(8)
 
 
 
BioAssay Types:
Literature(358)
 
 
 
 
 
Confirmatory(306)
 
 
 
 
 
Summary(24)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(205)
 
 
 
 
IC50(128)
 
 
 
EC50(66)
 
 
 
Ki(11)
 
 
Kd(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1113    Data Row: 1200   Total Pages: 60   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104234147]
EC50 8.4e-05Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-1 adrenergic receptor [AID246460, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
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2
[SID104234147]
EC50 8.4e-05Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA [AID317596, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
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3
[SID104234147]
EC50 8.4e-05Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay [AID344246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
4
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366404, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
5
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulation [AID387246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
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6
[SID104234147]
IC50 0.0001Inhibition of spontaneous contractions in isolated rat uterus [AID41474, Type: Literature]Beta-2 adrenergic receptor [gi:114768]
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7
[SID104234147]
IC50 0.0001Agonistic activity towards beta-2 adrenoceptor. IC50, the mean concentration required to produce 50% inhibition of uterine contraction [AID220922, Type: Literature]
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8
[SID104234147]
EC50 0.00084Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349760, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
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9
[SID104234147]
EC50 0.00084Agonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429598, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
10
[SID104234147]
EC50 0.00097Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-3 adrenergic receptor [AID246462, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
11
[SID104234147]
EC50 0.00097Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA [AID317595, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
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12
[SID104234147]
EC50 0.00097Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay [AID344247, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
13
[SID104234147]
EC50 0.00097Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349762, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
14
[SID104234147]
EC50 0.00097Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation [AID387245, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
15
[SID104234147]
EC50 0.00097Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366403, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
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16
[SID104234147]
EC50 0.0015In vitro beta-adrenergic activity against beta-1 adrenergic receptor by stimulation of rate of contraction of guinea pig atria [AID220909, Type: Literature]
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17
[SID104234147]
EC50 0.002Agonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429597, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
18
[SID104234147]
EC50 0.002Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-2 adrenergic receptor [AID246461, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
19
[SID104234147]
EC50 0.002Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay [AID344248, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
20
[SID104234147]
EC50 0.002Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349761, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View