Isoproterenol (CID 3779) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(96)
 
 
Inactive(148)
 
 
Inconclusive(38)
 
 
Unspecified(317)
 
 
Top Targets:
7TM GPCR Srsx(55)
 
 
 
 
7TM GPCR Srx(16)
 
 
 
p450(8)
 
 
Pyr redox dim(4)
 
 
 
 
Geminin(4)
 
 
 
BioAssay Types:
Literature(340)
 
 
 
 
 
Confirmatory(102)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
IC50(127)
 
 
 
Potency(101)
 
 
 
 
EC50(49)
 
 
 
Ki(11)
 
 
Kd(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 526    Data Row: 599   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104234147]
EC50 8.4e-05Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzymeimmuno assay [AID344246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
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2
[SID104234147]
EC50 8.4e-05Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzymeimmuno assay [AID344246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
3
[SID104234147]
EC50 8.4e-05Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzymeimmuno assay [AID344246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
4
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366404, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
5
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366404, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
6
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366404, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
7
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulation [AID387246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
8
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulation [AID387246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
9
[SID104234147]
EC50 8.4e-05Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulation [AID387246, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
10
[SID104234147]
EC50 8.4e-05Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA [AID317596, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
11
[SID104234147]
EC50 8.4e-05Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA [AID317596, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
12
[SID104234147]
EC50 8.4e-05Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA [AID317596, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
13
[SID104234147]
EC50 8.4e-05Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-1 adrenergic receptor [AID246460, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
14
[SID104234147]
EC50 8.4e-05Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-1 adrenergic receptor [AID246460, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
15
[SID104234147]
EC50 8.4e-05Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-1 adrenergic receptor [AID246460, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
16
[SID104234147]
IC50 0.0001Agonistic activity towards beta-2 adrenoceptor. IC50, the mean concentration required to produce 50% inhibition of uterine contraction [AID220922, Type: Literature]
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17
[SID104234147]
IC50 0.0001Inhibition of spontaneous contractions in isolated rat uterus [AID41474, Type: Literature]Beta-2 adrenergic receptor [gi:114768]
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18
[SID104234147]
EC50 0.00084Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349760, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
19
[SID104234147]
EC50 0.00084Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349760, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
20
[SID104234147]
EC50 0.00084Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349760, Type: Literature]Beta-1 adrenergic receptor [gi:48429211]
View
21
[SID104234147]
EC50 0.00084Agonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429598, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
22
[SID104234147]
EC50 0.00084Agonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429598, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
23
[SID104234147]
EC50 0.00084Agonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429598, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
24
[SID104234147]
EC50 0.00084Agonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429598, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
25
[SID104234147]
EC50 0.00097Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation [AID387245, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
26
[SID104234147]
EC50 0.00097Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation [AID387245, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
27
[SID104234147]
EC50 0.00097Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349762, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
28
[SID104234147]
EC50 0.00097Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349762, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
29
[SID104234147]
EC50 0.00097Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366403, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
30
[SID104234147]
EC50 0.00097Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366403, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
31
[SID104234147]
EC50 0.00097Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzymeimmuno assay [AID344247, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
32
[SID104234147]
EC50 0.00097Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzymeimmuno assay [AID344247, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
33
[SID104234147]
EC50 0.00097Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-3 adrenergic receptor [AID246462, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
34
[SID104234147]
EC50 0.00097Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-3 adrenergic receptor [AID246462, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
35
[SID104234147]
EC50 0.00097Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA [AID317595, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
36
[SID104234147]
EC50 0.00097Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA [AID317595, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
37
[SID104234147]
EC50 0.0015In vitro beta-adrenergic activity against beta-1 adrenergic receptor by stimulation of rate of contraction of guinea pig atria [AID220909, Type: Literature]
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38
[SID104234147]
EC50 0.002Agonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429597, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
39
[SID104234147]
EC50 0.002Agonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay [AID429597, Type: Literature]Beta-3 adrenergic receptor [gi:461604]
View
40
[SID104234147]
EC50 0.002Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-2 adrenergic receptor [AID246461, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
41
[SID104234147]
EC50 0.002Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-2 adrenergic receptor [AID246461, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
42
[SID104234147]
EC50 0.002Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-2 adrenergic receptor [AID246461, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
43
[SID104234147]
EC50 0.002Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-2 adrenergic receptor [AID246461, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
44
[SID104234147]
EC50 0.002Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366406, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
45
[SID104234147]
EC50 0.002Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366406, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
46
[SID104234147]
EC50 0.002Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366406, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
47
[SID104234147]
EC50 0.002Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation [AID366406, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
48
[SID104234147]
EC50 0.002Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349761, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
49
[SID104234147]
EC50 0.002Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349761, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View
50
[SID104234147]
EC50 0.002Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay [AID349761, Type: Literature]Beta-2 adrenergic receptor [gi:296439450]
View